local_hospital

Centro Hospitalar E Universitario De Coimbra E.P.E.

Address
Praceta Professor Mota Pinto, 3004-561 Coimbra, Portugal

Cardiovascular Diseases

The Centro Hospitalar E Universitario De Coimbra E.P.E. Neurology department is conducting research aimed at preventing and treating cerebrovascular events, with a focus on acute ischemic stroke and high‑risk transient ischemic attack. A key study evaluates the safety and efficacy of milvexian to lower the risk of recurrent stroke.

  • Acute Ischemic Stroke
  • High‑Risk Transient Ischemic Attack
  • Antithrombotic Therapy Development
  • Risk Reduction Strategies

Investigators are exploring novel anticoagulant approaches to improve outcomes for patients at high risk of cardiovascular complications.

Nervous System Diseases

In the realm of neurodegenerative and epileptic disorders, the site is testing innovative therapies for Alzheimer's disease and primary generalized tonic‑clonic seizures. One trial measures amyloid reduction with ABBV‑916 in early Alzheimer’s, while another assesses the impact of XEN1101 on seizure frequency.

  • Early Alzheimer’s Disease
  • Amyloid Targeting Strategies
  • Primary Generalized Tonic‑Clonic Seizures
  • Seizure Frequency Reduction

The multidisciplinary team aims to bring disease‑modifying treatments to patients with cognitive decline and epilepsy.

Virus Diseases

The hospital participates in an adaptive platform trial addressing COVID‑19, evaluating therapeutic options for both moderate and severe disease. A specific protocol compares baricitinib plus standard of care against placebo in immunocompromised patients with critical illness.

  • Moderate COVID‑19
  • Severe/Critical COVID‑19
  • Adaptive Pandemic Platform
  • Immunocompromised Patient Care

These efforts contribute to global knowledge on effective interventions during the pandemic and support vulnerable patient groups.

Site Overview

assignment
182
connected trials
corporate_fare
89
sponsors
science
320
IMPs

Activity Indicator

Last 6 months

15
Trials started
-25% vs previous period.
20
Trials started 6–12 months ago
182
Total trials linked
Highly Active
trending_downDeclining-25%
4
2
4
2
2
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 of 20 therapeutic areas and 15 of 320 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years

Top 40 of 310 compounds, ranked by number of trials.

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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
103
Sponsors (total)
89
Active sponsors
67

Sponsor Network

Top 67 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 84 other sites in Portugal

description
Trial volume
182
Outperforms 96% of sites
public
Therapeutic diversity
22areas
Outperforms 95% of sites
groups
Sponsor diversity
89sponsors
Outperforms 99% of sites

Therapeutic Area Benchmark — Portugal

Select a therapeutic area to compare against other sites in Portugal.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Portugal

Market Share

Country: Portugal

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Centro Hospitalar E Universitario De Coimbra E.P.E.

lock Showing 1 of 182 trials — the rest is available on a paid plan.

IMP list

lock Showing 1 of 320 compounds — the rest is available on a paid plan.

IMP Trials Status First start Last start
Pembrolizumab9Unknown2015-11-062025-09-18

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