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Centre Monticelli Paradis D Ophtalmologie

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Eye Diseases and Ocular Physiology

At Centre Monticelli Paradis D Ophtalmologie in Marseille, clinical research is focused on major ophthalmology conditions, especially age-related macular degeneration, diabetic macular edema, geographic atrophy, and other forms of retinal disease. The trials are designed to test new treatments, compare them with established care, and better understand long-term eye function and vision outcomes.

  • Testing new therapies for neovascular age-related macular degeneration and related retinal neovascular diseases
  • Evaluating treatments for diabetic macular edema and their impact on vision and retinal thickness
  • Studying approaches to slow geographic atrophy and preserve sight in dry AMD
  • Assessing safety, durability, and real-world usefulness of emerging ophthalmic treatments

The site’s research also includes work on uveitis, macular telangiectasia, and choroidal neovascularization, reflecting a broad effort to improve treatment effectiveness and long-term patient outcomes across retinal and inflammatory eye conditions.

Retinal Degeneration and Geographic Atrophy Research

This research area centers on progressive retinal damage, with a strong emphasis on geographic atrophy and dry age-related macular degeneration. Studies at the site are exploring whether new medicines can slow lesion growth, protect retinal tissue, and maintain visual function over time.

  • Investigating therapies for geographic atrophy secondary to AMD
  • Assessing whether new treatments can reduce the rate of retinal lesion expansion
  • Monitoring long-term safety of promising complement-targeted and other retinal therapies
  • Supporting better understanding of vision preservation in advanced macular disease

Several studies in this area aim to improve care for people living with slowly worsening central vision loss, with a focus on treatment effectiveness and sustained safety.

Macular Edema and Anti-VEGF Treatment Strategies

Another major focus is diabetic macular edema, where researchers are comparing eye treatments intended to reduce swelling, improve visual acuity, and lower the treatment burden for patients. The work includes both established therapies and newer options designed to offer longer-lasting control.

  • Comparing treatments for diabetic macular edema to improve vision outcomes
  • Evaluating options for patients with persistent or resistant retinal swelling
  • Studying ways to reduce the frequency of eye injections while maintaining benefit
  • Assessing the effectiveness of anti-VEGF and steroid-based approaches in retinal disease

These trials are aimed at finding practical, effective ways to manage chronic macular swelling and improve daily visual function for people with diabetes-related eye disease.

Innovative Ophthalmic Therapies and Long-Term Vision Outcomes

The site also contributes to research on newer ophthalmic therapies, including gene-based and sustained-delivery approaches for retinal disease. These studies are intended to test whether emerging treatments can offer durable control of neovascular AMD and related disorders while preserving vision.

  • Testing advanced treatments for neovascular age-related macular degeneration
  • Evaluating long-term safety and effectiveness of novel retinal therapies
  • Studying approaches that may reduce ongoing treatment burden for patients
  • Comparing newer interventions with standard anti-VEGF care

Overall, the research portfolio at this Marseille eye care center reflects a strong commitment to improving both immediate treatment response and long-term visual preservation in retinal disease.

Site Overview

assignment
26
connected trials
corporate_fare
18
sponsors
science
20
IMPs

Activity Indicator

Last 6 months

2
Trials started
0% vs previous period.
2
Trials started 6–12 months ago
26
Total trials linked
Highly Active
trending_flatStable0%
1
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 2 therapeutic areas and 15 of 20 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
12
Sponsors (total)
18
Active sponsors
10

Sponsor Network

Top 10 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 978 other sites in France

description
Trial volume
26
Outperforms 83% of sites
public
Therapeutic diversity
2areas
Outperforms 40% of sites
groups
Sponsor diversity
18sponsors
Outperforms 84% of sites

Therapeutic Area Benchmark — France

Select a therapeutic area to compare against other sites in France.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: France

Market Share

Country: France

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Centre Monticelli Paradis D Ophtalmologie

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Trial Sponsor Phase Status Start Date End Date
(22153) Randomized, Double-Masked, Active-Controlled, Phase 3 Study of the Efficacy and Safety of Aflibercept 8 mg in Macular Edema Secondary to Retinal Vein OcclusionBayer AGPhase IIINot RecruitingSep 2023May 2025

IMP list

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IMP Trials Status First start Last start
Ranibizumab7Unknown2021-10-222025-12-18

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