Centre hospitalier universitaire de Liege

The Centre hospitalier universitaire de Liege runs a strong program in digestive system diseases, especially Crohn’s disease and ulcerative colitis. Research here focuses on improving symptom control, mucosal and transmural healing, and long-term disease management with newer treatments and care strategies.

• Moderate to severe Crohn’s disease and ulcerative colitis
• Inflammatory bowel disease with postoperative recurrence or fistulizing disease
• Studies of treatment effectiveness, healing outcomes, and safer disease control

This work reflects a broad effort to improve daily quality of life and reduce relapse in people with chronic intestinal inflammation.

Medical oncology at this site includes extensive research in neoplasms, with a major focus on breast cancer, lung cancer, ovarian cancer, endometrial cancer, colorectal cancer, and gastroesophageal cancers. Many trials aim to test new cancer therapies, compare treatment options, and improve outcomes in advanced or hard-to-treat disease.

• Breast cancer, including HER2-positive, HER2-low, and hormone receptor-positive disease
• Non-small cell lung cancer, small cell lung cancer, and head and neck squamous cell carcinoma
• Ovarian, endometrial, colorectal, pancreatic, and urothelial cancers

The research portfolio is centered on testing targeted and immune-based approaches, as well as evaluating how well established treatments work in different cancer settings.

This site has a major research presence in hemic and lymphatic diseases, especially acute leukemias, multiple myeloma, myelodysplastic syndromes, and lymphomas. The studies are designed to improve frontline therapy, support remission, and help patients with relapsed or refractory blood cancers.

• Acute lymphoblastic leukemia and acute myeloid leukemia
• Follicular lymphoma, mantle cell lymphoma, diffuse large B-cell lymphoma, and related non-Hodgkin lymphomas
• Multiple myeloma, myelofibrosis, and myelodysplastic syndromes

Several trials also explore hematopoietic stem cell transplantation and immune-based strategies to improve long-term control of hematologic malignancies.

Another important area at Centre hospitalier universitaire de Liege is research in immune system diseases, skin and connective tissue diseases, and inflammatory joint conditions. Trials often aim to ease chronic inflammation, reduce flares, and improve patient-reported symptoms in long-lasting autoimmune disorders.

• Systemic lupus erythematosus, cutaneous lupus, and lupus nephritis
• Psoriasis, atopic dermatitis, hidradenitis suppurativa, and vitiligo
• Rheumatoid arthritis, psoriatic arthritis, and giant cell arteritis

These studies are aimed at better symptom relief, longer disease control, and more personalized treatment choices for people with chronic immune-mediated conditions.

The site also studies respiratory tract diseases, kidney diseases, and cardiovascular and metabolic disorders. Research includes chronic lung inflammation, fibrotic lung disease, kidney function preservation, and conditions linked to obesity, diabetes, and hypertension.

• Asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and progressive pulmonary fibrosis
• IgA nephropathy, chronic kidney disease, focal segmental glomerulosclerosis, and primary hyperoxaluria
• Obesity, type 2 diabetes, resistant hypertension, and atherosclerotic cardiovascular disease

Trials in this area are generally focused on improving long-term disease control, protecting organ function, and reducing complications.

Research at this hospital also covers virus diseases, bacterial infections, and complex care in transplant and intensive care settings. The studies address prevention, treatment effectiveness, and recovery in patients with serious infections or immune suppression.

• COVID-19, cytomegalovirus, Epstein-Barr virus, and herpes zoster
• Acute graft-versus-host disease and chronic graft-versus-host disease
• Sepsis, severe community-acquired pneumonia, and other critical infections

These trials are intended to improve infection control, support transplant outcomes, and strengthen care for vulnerable patients in hospital-based settings.

The research portfolio further includes nervous system diseases, eye diseases, and selected procedural and supportive care studies. This broad activity shows the site’s interest in both disease-specific therapies and practical improvements in patient care.

• Multiple sclerosis, Parkinson’s disease, stroke, and disorders of consciousness
• Thyroid eye disease and glaucoma
• Anesthesia, surgical procedures, and other diagnostic or therapeutic techniques

Across these topics, the emphasis is on evaluating effectiveness, improving function, and supporting better outcomes in specialized clinical care.