Centre Hospitalier Universitaire de la Réunion - Site Sud

At Centre Hospitalier Universitaire de la Réunion - Site Sud, research in neoplasms includes studies focused on aggressive brain cancers in the pediatric and adolescent setting. The trials aim to evaluate new treatment approaches and improve outcomes for patients with diffuse intrinsic pontine glioma and related diffuse midline gliomas.

• Children, adolescents and adults with newly diagnosed diffuse intrinsic pontine glioma and other diffuse midline gliomas
• Testing whether a new therapy can improve disease control when combined with standard care
• Improving survival outcomes in rare and hard-to-treat brain tumors

This area reflects a strong interest in developing better options for rare, high-risk cancers where treatment choices remain limited.

Clinical research in respiratory tract diseases is centered on non-small-cell lung cancer, including locally advanced, unresectable, and metastatic disease. These studies are designed to compare treatment effectiveness and explore more effective immunotherapy-based strategies for patients with advanced lung cancer.

• Locally advanced, unresectable, or metastatic non small cell lung cancer
• Previously untreated, PD-L1-selected non-small-cell lung cancer
• Comparing new immunotherapy combinations with established treatment options
• Evaluating overall survival and treatment benefit in first-line care

This work highlights a key focus on lung cancer treatment innovation, especially for patients who need improved first-line options.

Another important research area covers myeloproliferative neoplasms, a group of chronic blood cancers that can increase the risk of clotting complications. Studies here are aimed at preventing arterial and venous thrombosis and finding safer, more effective ways to protect high-risk patients.

• Philadelphia-negative myeloproliferative neoplasms
• Polycythemia vera, essential thrombocythemia, primary myelofibrosis, and prefibrotic myelofibrosis
• Testing whether one preventive treatment approach works better than another
• Reducing thrombo-embolic complications in high-risk patients

The Pneumologie department at this site supports research that extends beyond lung disease, contributing to broader cancer and blood disorder studies.