Centre Hospitalier Specialise Notre-Dame des Anges
- Address
- Rue Emile-Vandervelde 67, 4000 Liège, Belgium
Centre Hospitalier Specialise Notre-Dame des Anges - Depression and Mood Disorders Research
The Centre Hospitalier Specialise Notre-Dame des Anges is a specialized psychiatric research facility dedicated to advancing the treatment of complex mood disorders. The center focuses particularly on investigating novel therapeutic approaches for patients with treatment-resistant depression and those experiencing severe motivational symptoms that do not adequately respond to conventional antidepressant therapies.
- Major Depressive Disorder (MDD) with moderate-to-severe anhedonia
- Adjunctive therapy strategies for treatment-resistant depression
- Relapse prevention in patients with persistent depressive symptoms
The center conducts rigorous placebo-controlled studies evaluating aticaprant as an adjunctive treatment option combined with standard SSRI/SNRI antidepressants. Their research specifically targets patients with anhedonia—the inability to feel pleasure—who have shown inadequate response to current antidepressant therapy, addressing a critical unmet need in psychiatric care. Through both acute treatment trials and long-term extension studies, the center contributes valuable data on relapse prevention strategies and the safety profile of emerging pharmacological interventions for complex depressive disorders.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 10 by active trials.
No sponsors linked to active trials.
Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
- 1Janssen Cilag International2trials
Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 307 other sites in Belgium
Therapeutic Area Benchmark — Belgium
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Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Belgium
Market Share
Country: Belgium
Therapeutic Area Market Share
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Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Centre Hospitalier Specialise Notre-Dame des Anges
lock Showing 1 of 2 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| Adjunctive Aticaprant and Antidepressant Therapy for Relapse Prevention in Major Depressive Disorder with Moderate-to-Severe Anhedonia: A Randomized, Double-Blind Study | Janssen Cilag International | Phase III | Not Recruiting | Dec 2024 | Feb 2025 |
IMP list
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Aticaprant | 2 | Unknown | 2024-11-14 | 2024-12-04 |
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