Centre Hospitalier De Saint-Brieuc

At Centre Hospitalier De Saint-Brieuc, clinical trials in cardiovascular diseases and type 2 diabetes focus on improving outcomes for people with hypertension, established heart disease, and related complications. The research is centered on testing new treatment combinations and evaluating whether they can better prevent serious cardiovascular events.

• Studies in cardiovascular disease and type 2 diabetes
• Research on hypertension and heart failure risk reduction
• Evaluation of new therapies aimed at preventing major cardiac complications

These trials aim to support more effective long-term management for patients with complex cardiometabolic conditions.

The site is active in neoplasms research, with studies involving multiple myeloma, diffuse large B-cell lymphoma, and metastatic breast cancer. This work is designed to assess whether newer cancer treatments can improve disease control, deepen response, and extend progression-free survival.

• Studies in multiple myeloma and treatment strategies for newly diagnosed patients
• Research in lymphoma and breast cancer
• Testing modern cancer therapies to improve response and survival outcomes

These investigations reflect a strong interest in refining cancer care through more effective and better-targeted treatment approaches.

Clinical research here also covers immune system diseases and digestive disorders, including Crohn's disease and severe recurrent aphthous stomatitis. The trials are evaluating whether new therapies can reduce inflammation, relieve symptoms, and improve remission rates in patients with difficult-to-treat conditions.

• Studies in Crohn's disease and oral ulcer disorders
• Assessment of treatments aimed at controlling inflammation and symptoms
• Research focused on achieving sustained remission and better quality of life

This area highlights the site’s work in chronic inflammatory conditions where symptom control and durability of response are especially important.

The Service de cardiologie contributes to trials that extend beyond chronic disease management into anesthesia, critical care, and perioperative medicine. Current studies include patients requiring unplanned mechanical ventilation in the ICU and people undergoing colorectal surgery, with the goal of improving recovery and lowering postoperative complications.

• Research in intensive care for critically ill patients
• Studies in colorectal surgery to reduce surgical site infections
• Trials aimed at improving recovery and treatment safety in acute care settings

These projects support better care during high-risk hospital treatments and recovery periods.

The research portfolio also includes respiratory tract diseases and congenital or hereditary disorders, with studies in small cell lung cancer and hereditary hemochromatosis. The purpose is to explore new ways to maintain disease control in cancer and to assess therapies that may help manage excess iron in inherited metabolic disease.

• Studies in small cell lung cancer and inherited iron overload disorders
• Evaluation of treatments aimed at maintaining cancer control and reducing iron burden
• Research addressing both oncology and rare genetic disease needs

These trials show a broad interest in conditions that range from advanced cancer to uncommon hereditary diseases.

Additional trials at the site involve skin and connective tissue diseases, hemic and lymphatic diseases, and diagnostic and therapeutic techniques. They include work on chemotherapy-induced peripheral neuropathy and other supportive care questions, reflecting efforts to improve comfort, safety, and treatment experience for patients across different specialties.

• Studies related to supportive care and treatment-related symptoms
• Research in hematology and dermatology-related conditions
• Trials aimed at improving symptom relief and treatment tolerability

This broader research activity complements the site’s disease-focused trials by addressing real-world challenges faced during treatment.