Casa di Cura Villa Maria
- Address
- Contrada Pozzillo, Mirabella Eclano (AV), 83036 Mirabella Eclano, Italy
Casa di Cura Villa Maria - Colorectal Cancer Research Center
Casa di Cura Villa Maria is a specialized clinical research facility focused on advancing treatment strategies for metastatic colorectal cancer. The center demonstrates particular expertise in precision oncology through molecular profiling and targeted therapy approaches for patients with specific genetic biomarkers.
- First-line treatment optimization for RAS/B-RAF wild-type metastatic colorectal cancer
- Intermittent versus continuous targeted therapy regimens with anti-EGFR agents
- Biomarker research for primary and secondary resistance mechanisms
- Quality of life and safety assessments in advanced gastrointestinal malignancies
The center's research emphasizes innovative dosing strategies combining Panitumumab with FOLFIRI chemotherapy for left-sided tumors, investigating whether intermittent treatment schedules can maintain efficacy while improving patient tolerability. Their comprehensive approach includes correlative studies examining tissue and blood biomarkers to better understand treatment response and resistance patterns in unresectable metastatic disease.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 2 by active trials.
lock +1 more on a paid plan
Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 566 other sites in Italy
Therapeutic Area Benchmark — Italy
Select a therapeutic area to compare against other sites in Italy.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: Italy
Market Share
Country: Italy
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Casa di Cura Villa Maria
lock Showing 1 of 3 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| A phase II, open label, multicenter trial investigating Irinotecan plus cetuximab rechallenge compared with trifluridine/tipiracil plus bevacizumab as third line treatment in circulating tumor DNA molecularly selected metastatic colorectal cancer: the ROMANCE-GOIM trial | Gruppo Oncologico Dell'Italia Meridionale | Phase II | Recruiting | Mar 2026 | — |
IMP list
lock Showing 1 of 9 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Bevacizumab | 2 | Unknown | 2025-07-21 | 2026-03-11 |
Request feasibility information
Ask this centre about capacity, equipment and patient population.
Upgrade this site to Business Plan
Own the profile, publish your feasibility data and reach sponsors directly.
Is something out of date?
Tell us what needs correcting and we'll update this profile.
lock Available to Business plan sites only.