Brain Research Center Den Bosch B.V.
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Brain Research Center Den Bosch B.V.
Brain Research Center Den Bosch B.V. is a specialized clinical research facility focused on neurodegenerative diseases and cognitive disorders. The center has established expertise in conducting complex clinical trials for patients with various forms of dementia, with particular emphasis on early-stage interventions and novel therapeutic approaches targeting underlying disease mechanisms.
- Alzheimer's disease research, including mild cognitive impairment (MCI) and mild dementia stages
- Dementia with Lewy Bodies (DLB) clinical investigations
- Anti-tau monoclonal antibody therapies and P38 kinase inhibitors
- Cognitive and functional assessment using standardized rating scales
The research center demonstrates proficiency in evaluating both safety and efficacy outcomes for innovative treatments, including immunotherapy approaches and kinase inhibitor therapeutics. Their clinical trials utilize validated assessment tools such as the Clinical Dementia Rating-Sum of Boxes (CDR-SB) and integrated Alzheimer's Disease Rating Scale (iADRS) to measure treatment effects on cognition and daily functioning. The facility's expertise extends to specialized diagnostic procedures including DaTscan imaging and polysomnography for accurate disease characterization.
Site Overview
Activity Indicator
Last 6 months
Trial Flow
How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.
Top 4 therapeutic areas and 15 of 35 IMPs, ranked by number of trials.
Compounds & Molecules Timeline
The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.
Sponsor & Partnership
Top sponsors by active trials, and the ones that have come back for more than one study.
Sponsor Network
Top 15 by active trials.
- 1Novo Nordisk A/S2active
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Partnership History
Sponsors with repeated collaboration (≥ 2 trials).
- 1Novo Nordisk A/S4trials
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Sponsor Network Graph
How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.
Country Benchmark
Compared to 271 other sites in The Netherlands
Therapeutic Area Benchmark — The Netherlands
Select a therapeutic area to compare against other sites in The Netherlands.
Competitor Comparison
Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.
Country: The Netherlands
Market Share
Country: The Netherlands
Therapeutic Area Market Share
Select a therapeutic area to view its disease coverage breakdown.
Heat Maps & Advanced Analytics
How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.
Other Trials in Brain Research Center Den Bosch B.V.
lock Showing 1 of 32 trials — the rest is available on a paid plan.
| Trial | Sponsor | Phase | Status | Start Date | End Date |
|---|---|---|---|---|---|
| A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants with Early Alzheimer's Disease | Denali Therapeutics Inc. | Phase I | Recruiting | Apr 2026 | — |
IMP list
lock Showing 1 of 35 compounds — the rest is available on a paid plan.
| IMP | Trials | Status | First start | Last start |
|---|---|---|---|---|
| Florquinitau (18F) | 4 | Unknown | 2023-04-13 | 2025-11-12 |
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