Azienda Ospedaliero Universitaria Di Sassari

At Azienda Ospedaliero Universitaria Di Sassari, cardiology trials focus on cardiovascular disease, heart failure, and atrial fibrillation, with additional work in atherosclerotic disease and myocardial infarction. These studies are mainly designed to test new treatment strategies, reduce major cardiac events, and improve outcomes after procedures or in high-risk patients.

• Preventing major cardiovascular events in people with established vascular disease or elevated risk
• Improving treatment for heart failure with preserved or mildly reduced ejection fraction and obesity
• Evaluating antiplatelet strategies after left atrial appendage closure
• Assessing therapies for pulmonary hypertension and related circulatory disorders

Several projects also explore biomarkers and anti-inflammatory approaches to better understand how heart and vessel disease develops and responds to treatment.

Respiratory research at this site includes chronic obstructive pulmonary disease, severe asthma, idiopathic pulmonary fibrosis, pulmonary arterial hypertension, and pulmonary hypertension associated with interstitial lung disease. The trials aim to evaluate new therapies that may ease symptoms, lower exacerbations, and slow decline in lung function.

• Testing treatments for COPD and reducing flare-ups in symptomatic patients
• Studying options for severe asthma with eosinophilic inflammation
• Evaluating approaches for idiopathic pulmonary fibrosis and lung volume loss
• Exploring therapies for pulmonary hypertension and exercise limitation

These studies reflect a strong interest in improving breathing-related quality of life through better long-term disease control.

The oncology portfolio at Azienda Ospedaliero Universitaria Di Sassari covers colorectal cancer, breast cancer, lung cancer, and blood cancers such as acute myeloid leukemia, chronic myeloid leukemia, and myelodysplastic syndromes. The main goal is to improve treatment effectiveness, refine patient selection, and support deeper responses to therapy.

• Testing new combinations and sequencing strategies in metastatic colorectal cancer
• Evaluating targeted and immune-based approaches in non-small cell lung cancer and small cell lung cancer
• Studying therapies for early breast cancer at high risk of recurrence
• Assessing treatment intensification and transplant-related strategies in acute myeloid leukemia and myelodysplastic syndromes

Research in this area includes efforts to improve survival, reduce residual disease, and match therapy more closely to tumor biology.

Trials in virus diseases and related internal medicine areas address HIV, chronic hepatitis B, and HIV/hepatitis B coinfection. These studies are focused on better viral control, long-term safety, and the possibility of stronger treatment responses in people already receiving standard care.

• Testing new antiviral strategies for HIV in treatment-naïve adults
• Evaluating therapies intended to improve outcomes in chronic hepatitis B
• Studying approaches for patients with HIV and hepatitis B coinfection
• Exploring ways to support durable viral suppression and functional cure goals

These projects combine infectious disease research with a practical focus on better long-term disease management.

The site also participates in studies across eye diseases, mental disorders, and selected general health topics. Research includes glaucoma, major depressive disorder, and women’s health questions, with an emphasis on symptom relief, quality of life, and better supportive care.

• Investigating treatments to preserve vision in glaucoma
• Evaluating rapid symptom reduction for adolescents with major depressive disorder and suicidal thoughts
• Studying menstrual control and tolerability in women’s health research
• Supporting broader diagnostic and therapeutic innovation across multiple specialties

These studies show a broad clinical research profile that extends beyond cardiology into areas where new options may improve daily functioning and patient well-being.