local_hospital

Axon Clinical s.r.o.

Address
Ostrovskeho 253/3, Smichov, 150 00 Prague, Czechia

Axon Clinical s.r.o. - Advanced Ophthalmology, Neurology & Gastroenterology Research Center

Axon Clinical s.r.o. is a specialized clinical research center with extensive expertise in conducting multi-phase trials across diverse therapeutic areas. The center demonstrates particular strength in ophthalmological conditions, with a comprehensive focus on age-related macular degeneration and its variants, including geographic atrophy, neovascular AMD, and diabetic macular edema. Their ophthalmology portfolio encompasses innovative intravitreal therapies, complement inhibitors, and novel drug delivery systems.

  • Geographic Atrophy and Age-Related Macular Degeneration: Multiple Phase 2/3 trials evaluating complement inhibitors, visual function preservation, and long-term safety extensions
  • Neurological Disorders: Parkinson's disease motor fluctuation studies and migraine prevention/acute treatment trials, including novel CGRP antagonists and botulinum toxin therapies
  • Inflammatory Bowel Disease: Comprehensive research in Crohn's disease and ulcerative colitis, featuring biologics, JAK inhibitors, and long-term maintenance studies
  • Retinal Vascular Diseases: Advanced trials in diabetic macular edema and neovascular AMD with anti-VEGF agents and combination therapies

The center's research infrastructure supports complex trial designs including double-masked randomized controlled studies, open-label extensions, and dose-finding protocols. With experience spanning rare conditions such as SORD deficiency and thyroid eye disease, alongside high-prevalence diseases, Axon Clinical demonstrates versatility in managing diverse patient populations and sophisticated endpoint assessments including endoscopic evaluations, fundus autofluorescence imaging, and motor function diaries.

Site Overview

assignment
46
connected trials
corporate_fare
28
sponsors
science
35
IMPs

Activity Indicator

Last 6 months

3
Trials started
-62% vs previous period.
8
Trials started 6–12 months ago
46
Total trials linked
Highly Active
trending_downDeclining-62%
2
1
Mar
Apr
May
Jun
Jul
Aug

Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status

Top 5 therapeutic areas and 15 of 35 IMPs, ranked by number of trials.

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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
19
Sponsors (total)
28
Active sponsors
13

Sponsor Network

Top 13 by active trials.

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Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

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Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 634 other sites in Czechia

description
Trial volume
46
Outperforms 96% of sites
public
Therapeutic diversity
5areas
Outperforms 91% of sites
groups
Sponsor diversity
28sponsors
Outperforms 97% of sites

Therapeutic Area Benchmark — Czechia

Select a therapeutic area to compare against other sites in Czechia.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Czechia

Market Share

Country: Czechia

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in Axon Clinical s.r.o.

lock Showing 1 of 46 trials — the rest is available on a paid plan.

Trial Sponsor Phase Status Start Date End Date
(22153) Randomized, Double-Masked, Active-Controlled, Phase 3 Study of the Efficacy and Safety of Aflibercept 8 mg in Macular Edema Secondary to Retinal Vein OcclusionBayer AGPhase IIINot RecruitingSep 2023May 2025

IMP list

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IMP Trials Status First start Last start
Aflibercept7Unknown2021-08-272026-06-22

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