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AST Macerata

Address
Via Annibali,31/L, Province of Macerata, Italy

AST Macerata - Breast Cancer Research Center

AST Macerata is a clinical research center dedicated to advancing treatment strategies for aggressive forms of breast cancer. The center specializes in evaluating novel immunotherapy approaches for high-risk patient populations, with particular emphasis on improving long-term survival outcomes through adjuvant treatment protocols.

  • Triple negative breast cancer immunotherapy trials
  • Anti-PD-L1 antibody therapy research
  • Adjuvant treatment strategies for high-risk breast cancer

The center's research focuses on triple negative breast cancer, one of the most challenging breast cancer subtypes to treat. Through participation in the A-Brave trial, AST Macerata is investigating whether one year of adjuvant Avelumab, an anti-PD-L1 antibody, can improve disease-free survival in patients who have completed curative treatment including surgery and chemotherapy. This work represents a critical effort to expand therapeutic options for patients with high-risk disease following both neoadjuvant and adjuvant chemotherapy approaches.

Site Overview

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connected trial
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sponsor
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IMP

Activity Indicator

Last 6 months

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Trials started
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Trials started 6–12 months ago
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Total trials linked
Low Activity
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Trial Flow

How this site's trials are distributed across therapeutic areas and active substances (IMPs), and how they're positioned within their overall lifecycle status. Flow thickness represents the number of unique trials.

Therapeutic areaarrow_forwardIMParrow_forwardLifecycle status
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Compounds & Molecules Timeline

The time span of clinical-trial activity for the main active substances (IMPs) studied at this site over the last 8 years. Each bar runs from the earliest trial start to the most recent end; a substance with a trial still open has no recorded end and is shown as ongoing.

Trial span Ongoing Showing last 8 years
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Sponsor & Partnership

Top sponsors by active trials, and the ones that have come back for more than one study.

Active trials
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Sponsors (total)
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Sponsor Network

Top 10 by active trials.

No sponsors linked to active trials.

Partnership History

Sponsors with repeated collaboration (≥ 2 trials).

No repeated partnerships found.

Sponsor Network Graph

How sponsors and therapeutic areas connect across this site's active trials: each link is at least one active trial shared between them, and bigger nodes mean more activity. Click a node to see its exact connections.

Country Benchmark

Compared to 566 other sites in Italy

description
Trial volume
1
Outperforms 1% of sites
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Therapeutic diversity
1areas
Outperforms 1% of sites
groups
Sponsor diversity
1sponsors
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Therapeutic Area Benchmark — Italy

Select a therapeutic area to compare against other sites in Italy.

Competitor Comparison

Similar sites in the same country running a comparable number of trials (within ±30%), scored on how closely their trial portfolios match this one. Higher percentages mean a more similar profile.

Country: Italy

Market Share

Country: Italy

Therapeutic Area Market Share

Select a therapeutic area to view its disease coverage breakdown.

Heat Maps & Advanced Analytics

How often specific conditions appear in trials across this site and comparable sites from the same country. Each row is a site, each column a condition, and each cell the number of trials on it — darker means more activity.

Other Trials in AST Macerata

Trial Sponsor Phase Status Start Date End Date
Phase III Randomized Trial of Adjuvant Avelumab in High-Risk Triple Negative Breast Cancer Post-Curative TreatmentUniversita Degli Studi Di PadovaPhase IIINot RecruitingJun 2016Oct 2025

IMP list

IMP Trials Status First start Last start
Avelumab1Unknown2016-06-162016-06-16

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