Assistance Publique Hopitaux De Paris

At Assistance Publique Hopitaux De Paris, the Service de Dermatologie is conducting research in skin and connective tissue diseases focused mainly on atopic dermatitis, discoid lupus, subacute cutaneous lupus erythematosus, and inflammatory hepatic adenomas. These studies are designed to test new treatment options and improve long-term disease control for patients with chronic inflammatory conditions.

• Testing targeted therapies for atopic dermatitis and related inflammatory skin disorders
• Evaluating treatment strategies for active discoid lupus and subacute cutaneous lupus erythematosus
• Studying approaches to reduce the size of inflammatory hepatic adenomas

This area reflects a strong dermatology-led focus on immune-driven disease and personalized care.

The site is also active in immune system diseases and broader autoimmune diseases, with trials addressing ANCA-associated vasculitis and systemic sclerosis. The goal is to assess whether new therapies can better control inflammation, protect organ function, and ease disease burden.

• Improving outcomes in ANCA-associated vasculitis
• Evaluating symptom control in systemic sclerosis
• Exploring immune-modulating treatments for chronic autoimmune conditions

This research combines clinical care with studies aimed at more effective and better-tolerated immune therapies.

In respiratory tract diseases and otorhinolaryngologic diseases, trials at this Paris site include non-small cell lung cancer, head and neck squamous cell carcinoma, and severe community-acquired pneumonia. The research is centered on testing whether new combinations and treatment approaches can improve survival and disease control in serious respiratory and cancer conditions.

• Assessing new treatment approaches for non-small cell lung cancer
• Studying therapy options for head and neck cancer
• Evaluating treatments for severe pneumonia

These studies span both infectious and oncologic respiratory care, showing broad expertise in complex lung and upper airway diseases.

The site conducts important work in virus diseases, especially HIV-1 infection and pre-exposure prophylaxis for people at risk. Research here is aimed at improving prevention, maintaining viral control, and evaluating the safety and effectiveness of treatment switches or preventive regimens.

• Testing prevention strategies for HIV-1 infection
• Evaluating treatment-switch options for people living with HIV-1
• Studying ways to support long-term prevention in high-risk populations

This research reflects a practical focus on real-world HIV care and prevention.

The clinical trial portfolio also includes cardiovascular diseases, digestive system diseases, and male urogenital diseases. Current studies examine uncontrolled hypertension in chronic kidney disease, fertility-related care, and inflammatory conditions affecting the liver. The purpose is to improve disease management, reduce complications, and support better patient outcomes across several organ systems.

• Improving blood pressure control in chronic kidney disease
• Supporting fertility treatment in in vitro fertilization and ICSI care
• Investigating inflammatory conditions in the digestive system

At Assistance Publique Hopitaux De Paris, this cross-disciplinary work connects dermatology with broader internal medicine and reproductive health research.