Acibadem City Clinic University Multiprofile Hospital For Active Treatment EOOD

At Acibadem City Clinic University Multiprofile Hospital For Active Treatment EOOD in Sofia, much of the research focuses on digestive system diseases, especially ulcerative colitis and Crohn’s disease. These studies are exploring new ways to induce and maintain remission, improve symptoms, and better control long-term disease activity.

• Testing new therapies for moderately to severely active ulcerative colitis
• Evaluating treatments for Crohn’s disease to improve remission and endoscopic outcomes
• Studying long-term safety and effectiveness of IBD treatments

This area includes both treatment-focused research and studies aimed at improving disease control for patients living with chronic intestinal inflammation.

The site also takes part in clinical trials in cardiovascular diseases, with a strong emphasis on atherosclerotic cardiovascular disease, heart failure, hypertrophic cardiomyopathy, and pulmonary hypertension. The research is designed to test new options for reducing major heart-related events, improving symptoms, and supporting better quality of life.

• Assessing treatments for heart failure, including preserved and reduced ejection fraction forms
• Studying therapies for atherosclerotic cardiovascular disease and elevated lipoprotein(a)
• Evaluating approaches for hypertrophic cardiomyopathy and pulmonary hypertension

This cardiovascular portfolio reflects a broad effort to improve prevention and management of serious heart and circulation-related conditions.

Research at the hospital includes trials in immune system diseases and nervous system diseases, particularly multiple sclerosis. These studies are examining new therapies that may slow disability progression, reduce relapses, and offer better control of chronic inflammatory disease.

• Investigating treatments for relapsing and nonrelapsing forms of multiple sclerosis
• Exploring immune-targeted therapies for inflammatory conditions
• Supporting research into safer and more effective long-term disease control

The work in this area highlights the site’s involvement in therapies that target both immune activity and neurological outcomes.

The Gastroenterology Clinic is also involved in trials for virus diseases and liver-related conditions, including chronic hepatitis B, primary biliary cholangitis, and severe forms of cirrhosis with acute-on-chronic liver failure. These studies aim to improve treatment effectiveness, safety, and outcomes in complex liver disease.

• Testing new strategies for chronic hepatitis B in patients already receiving standard care
• Evaluating treatments for primary biliary cholangitis
• Studying therapies for advanced liver disease and acute-on-chronic liver failure

This research supports ongoing efforts to develop better options for patients with serious hepatic and viral illnesses.

Several trials at this hospital/clinic examine the role of inflammation across different diseases, including chronic kidney disease linked with cardiovascular risk and inflammatory burden. The studies are focused on understanding whether targeting inflammation can lower complications and improve clinical outcomes.

• Studying inflammation-related risk in cardiovascular and kidney disease
• Assessing therapies intended to reduce major adverse cardiovascular events
• Exploring links between immune activity and chronic organ disease

This area shows a growing interest in treatments that address shared inflammatory pathways across multiple chronic conditions.