Zbigniew N.
- Country
- Poland
- Department
- Klinika Nowotworów Piersi i Chirurgii Rekonstrukcyjnej
Research Overview
- An Open-label, Randomized, Phase 2/3 Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction of Clinical Benefit With First-line Chemotherapy Plus Pembrolizumab in Participants With Locally Recurrent Inoperable or Metastatic Triple Negative Breast Cancer (TNBC) (KEYLYNK 009)
- Phase III Trial of BNT327 plus Combination Chemotherapy versus Placebo plus Chemotherapy in Patients with Previously Untreated Metastatic or Locally Recurrent Triple-Negative Breast Cancer
- Study of Inavolisib with Trastuzumab and Pertuzumab as Maintenance Therapy in Patients with HER2‑Positive PIK3CA‑Mutated Locally Advanced or Metastatic Breast Cancer
Data & Insights
Has run more than one trial at 579 of 912 partner sites.
Specializations
Advanced Breast Cancer Research
Specializes in investigating treatments for hormone receptor-positive (HR+) and HER2-negative breast cancer, with particular focus on novel therapeutic combinations and targeted approaches.
- Endocrine therapy resistance
- Advanced metastatic disease
- CDK4/6 inhibitor combinations
Explores innovative treatment pathways including targeted therapies like capivasertib and giredestrant.
Early-Stage Breast Cancer
Focuses on developing treatments for early-stage HER2-positive and triple-negative breast cancer, with emphasis on adjuvant and neoadjuvant therapeutic approaches.
- Post-operative treatment optimization
- High-risk disease management
- Immunotherapy applications
Investigates novel therapeutic strategies including antibody-drug conjugates and targeted immunotherapies.
Precision Medicine Approaches
Specializes in biomarker-driven treatment strategies and personalized therapeutic approaches for breast cancer patients.
- PIK3CA mutation targeting
- ESR1 mutation analysis
- Treatment resistance mechanisms
Conducts research on molecular profiling and targeted therapy selection for optimal treatment outcomes.
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