Zaira Raquel P. B.
- Country
- Spain
- Department
- Infectious Diseases Department
Research Overview
- An interventional efficacy and safety Phase 3 double-blind 2-arm study to investigate IV followed by oral fosmanogepix compared with IV caspofungin followed by oral fluconazole in adult participants with candidemia and/or invasive candidiasis.
- Phase 3 Study on the Efficacy and Safety of Fosmanogepix in Adult Patients with Invasive Mold Infections by Aspergillus, Fusarium, and Multidrug-Resistant Molds
Data & Insights
Has run more than one trial at 24 of 56 partner sites.
Specializations
Inflammatory Bowel and Autoimmune Disease
Clinical research activity includes inflammatory bowel disease and related immune-mediated conditions, with a particular focus on Crohn’s disease and ulcerative colitis. The investigator is also involved in studies of systemic inflammatory disorders affecting joints and connective tissue.
- Crohn’s disease
- Ulcerative colitis
- Psoriatic arthritis
- Axial spondyloarthritis
- Rheumatoid arthritis
Additional interests extend to systemic lupus erythematosus and Sjögren’s syndrome, reflecting a broad therapeutic involvement in chronic immune dysregulation.
Oncology and Solid Tumors
The investigator participates in oncology research spanning breast cancer, lung cancer, melanoma, and other advanced solid malignancies. This includes therapeutic interest in tumor subtypes defined by receptor status and molecular alterations.
- Breast cancer
- Non-small cell lung cancer
- Melanoma
- Urothelial carcinoma
- Gastroesophageal cancer
Research activity also covers lymphoma and myelodysplastic syndromes, supporting work across both solid and hematologic malignancies.
Cardiovascular and Metabolic Disorders
Clinical trial involvement includes atherosclerotic cardiovascular disease, heart failure, and lipid-related risk conditions. The investigator’s therapeutic scope also reaches thromboembolic prevention and rhythm-related cardiovascular disease.
- Atherosclerotic cardiovascular disease
- Heart failure
- Atrial fibrillation
- Acute ischemic stroke
- Dyslipidemia
Related areas include hypertriglyceridemia, myocardial infarction, and cardiometabolic risk reduction.
Nephrology and Renal Immune Disease
The investigator is active in renal research centered on chronic kidney disease and immune-mediated glomerular disorders. These studies include conditions with proteinuric kidney injury and complement-driven renal inflammation.
- IgA nephropathy
- Focal segmental glomerulosclerosis
- Complement-mediated kidney disease
- Lupus nephritis
- Membranous nephropathy
Therapeutic interest also extends to end-stage kidney disease and renal complications associated with cardiovascular and autoimmune conditions.
Infectious Diseases and Antimicrobial Therapy
Within the Infectious Diseases Department, the investigator is involved in trials addressing bacterial, fungal, and viral infections, including severe and recurrent disease. The portfolio includes treatment strategies for systemic infections and resistant pathogens.
- Candidemia
- Clostridioides difficile infection
- Severe gram-negative bacterial infections
- Staphylococcus aureus bacteraemia
- HIV infection
Additional work includes pneumonia, infective endocarditis, and other complex infectious syndromes managed at Hospital Universitario Virgen Macarena.
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