Yannick G.
- Country
- France
- Department
- Pôle Urgence Pasteur
Research Overview
Data & Insights
Has run more than one trial at 0 of 23 partner sites.
Specializations
Oncology – Solid Tumors
Research focuses on advanced malignant neoplasms of the gastrointestinal tract, prostate, lung, pancreas and head‑and‑neck regions.
- unresectable metastatic colorectal cancer
- metastatic hormone‑naïve prostate cancer
- BRAFV600E‑mutant non‑small cell lung cancer
- pancreatic adenocarcinoma
- head and neck squamous cell carcinoma
The investigator contributes to therapeutic strategies that integrate targeted agents, immunotherapies and novel combination regimens.
Hematology – Acute Leukemia and Lymphoma
Investigations address frontline and salvage therapies for adult acute lymphoblastic leukemia, acute myeloid leukemia and primary central nervous system lymphoma.
- younger adult acute lymphoblastic leukemia
- adult acute myeloid leukemia
- primary central nervous system lymphoma
- blinatumomab‑based frontline regimens
- isotuximab integration in T‑ALL
Efforts aim to improve survival through immunotherapy, molecularly guided transplantation and optimized chemotherapy dosing.
Neurology – Neurodegenerative and Demyelinating Disorders
Studies target cognitive and psychiatric manifestations of neurodegeneration and inflammatory demyelination.
- Alzheimer’s disease psychosis
- adult brainstem glioma progression
- relapsing multiple sclerosis
- ischemic stroke outcomes
- neurocognitive effects of ADHD therapies
Therapeutic exploration includes monoclonal antibodies, disease‑modifying agents and neuroprotective strategies.
Cardiovascular and Renal Medicine
Clinical work includes acute myocardial infarction, chronic heart failure, stroke and advanced chronic kidney disease with cardiovascular risk.
- acute myocardial infarction management
- chronic heart failure optimization
- low‑dose rivaroxaban in chronic kidney disease
- cardiovascular outcome improvement in dialysis patients
- stroke reperfusion strategies
Research evaluates anticoagulation, novel lipid‑lowering agents and integrated heart‑kidney care pathways.
Gastrointestinal & Immune‑Mediated Inflammatory Diseases
Focus is on inflammatory bowel disease, rheumatoid arthritis and related systemic inflammatory conditions.
- Crohn’s disease biologic sequencing
- ulcerative colitis maintenance therapy
- rheumatoid arthritis rituximab optimization
- polymyalgia rheumatica glucocorticoid tapering
- immune thrombocytopenia treatment strategies
The investigator assesses combination regimens, dose‑adjusted biologics and real‑world effectiveness.
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