Yann M.
- Country
- France
- Department
- Medical Oncology
Research Overview
- TAILORswitch (PADA-2): ctDNA‑guided switch to camizestrant plus abemaciclib in ER‑positive HER2‑negative metastatic breast cancer
- Phase III Multicentric Study on Chemotherapy Efficacy in Stage III Colorectal Cancer with Positive ctDNA Post-Surgery Using Irinotecan and Drug Combination
- Phase III Randomized Controlled Trial Evaluating Tinengotinib Versus Physician's Choice in FGFR-Altered, Chemotherapy- and FGFR Inhibitor-Refractory Cholangiocarcinoma
Data & Insights
Has run more than one trial at 115 of 241 partner sites.
Specializations
Gastrointestinal Oncology
The investigator demonstrates significant expertise in treating colorectal cancers, with particular focus on colon carcinoma and BRAF V600E-mutated cases. Their research extends to ampullary adenocarcinoma and cholangiocarcinoma.
- Colon cancer management
- Biliary tract malignancies
- Targeted therapy approaches
Special attention is given to personalized treatment strategies using molecular markers and genetic mutations.
Precision Medicine
The investigator specializes in circulating tumor DNA analysis and its application in treatment decision-making. Their work includes minimal residual disease detection and monitoring through blood-based biomarkers.
- Liquid biopsy applications
- Molecular diagnostics
- Personalized treatment selection
Focus includes using molecular profiling to guide adjuvant therapy decisions.
Breast Cancer Research
The investigator conducts research in hormone receptor-positive breast cancer, specifically focusing on HER2-negative metastatic disease. Their work involves novel therapeutic combinations including targeted therapies.
- Endocrine therapy resistance
- Novel drug combinations
- Biomarker-driven treatment
Expertise includes investigating treatment strategies for advanced breast cancer.
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