Yann G.
- Country
- France
- Department
- 3302: Medical Oncology
Research Overview
- TRANSCRIPT: An open label, controlled, randomized multicentric international study evaluating the benefit of autologous stem cell transplantation after complete response in frontline setting patients with T cell-lymphoma
- A Phase 1-2, Open-Label Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Activity of Tolinapant in Combination with Oral Decitabine/Cedazuridine and Oral Decitabine/Cedazuridine Alone in Subjects with Relapsed/Refractory Peripheral T-cell Lymphoma
- Phase 2 Evaluation of Valemetostat Tosylate Monotherapy in Relapsed/Refractory Peripheral T-Cell Lymphoma Patients
Data & Insights
Has run more than one trial at 55 of 211 partner sites.
Specializations
T-Cell Lymphoma Research
The investigator specializes in treating peripheral T-cell lymphoma (PTCL), with particular emphasis on relapsed and refractory cases. Their work encompasses various PTCL subtypes including PTCL-NOS, PTCL-TFH, and ALCL.
- Novel therapeutic combinations
- Maintenance therapy approaches
- KIR3DL2-targeted treatments
Their research extends to rare T-cell lymphoma variants including hepatosplenic T-cell lymphoma and enteropathy-associated T-cell lymphoma.
Transplantation Studies
The investigator focuses on evaluating autologous stem cell transplantation outcomes in lymphoma patients. Their work examines the effectiveness of transplantation specifically in patients achieving complete response after induction therapy.
- Response-based treatment strategies
- Post-transplant survival outcomes
- PET-CT response assessment
Their research incorporates modern response criteria and imaging-based evaluation methods.
Chronic Lymphocytic Conditions
The investigator studies treatment approaches for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Their research explores innovative drug combinations and duration-optimized treatment protocols.
- MRD-guided therapy
- Novel drug combinations
- Fixed-duration treatments
Their work includes evaluation of targeted therapies including venetoclax and obinutuzumab combinations.
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