Xu-Shan S.
- Country
- France
- Department
- Radiotherapy
Research Overview
- Evaluation of Lymphocyte-Sparing Radiotherapy and All-Trans Retinoic Acid in Lateralized Oropharyngeal, Laryngeal, and Hypopharyngeal Squamous Cell Carcinoma
- Phase III Study on Laryngeal Preservation in Locally Advanced Squamous Cell Carcinomas of the Larynx or Hypopharynx: Comparing Induction Chemotherapy with Cisplatin, 5-Fluorouracil, and Docetaxel Followed by Radiotherapy Versus Concomitant Radiotherapy with Cisplatin.
- Phase III Randomized Trial of Avelumab, Cetuximab, and Radiotherapy Versus Standard Care in Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Data & Insights
Has run more than one trial at 67 of 120 partner sites.
Specializations
Head and Neck Oncology
This investigator specializes in treating head and neck cancers, with particular expertise in squamous cell carcinomas affecting various anatomical sites including the larynx, hypopharynx, and salivary glands.
- Salivary Gland Tumors
- Sinus Malignancies
- Laryngeal Cancer
The investigator's work encompasses both operable and non-operable cases, focusing on organ preservation strategies.
Therapeutic Approaches
The investigator explores innovative combinations of radiotherapy and chemotherapy treatments, including targeted therapeutic agents and immunotherapy approaches.
- Combined Modality Treatment
- Targeted Therapy Integration
- Immunotherapy Applications
A particular focus lies in evaluating treatment efficacy through survival metrics and organ function preservation.
Clinical Innovations
The investigator studies advanced therapeutic combinations incorporating novel agents such as cetuximab and nivolumab alongside conventional treatments.
- Laryngeal Preservation Techniques
- Advanced Disease Management
- Treatment Optimization Strategies
Research efforts concentrate on improving survival outcomes while maintaining organ function and quality of life.
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