Xavier V. M.
- Country
- Belgium
- Department
- Pneumology
Research Overview
Data & Insights
Has run more than one trial at 3 of 55 partner sites.
Specializations
Thoracic Oncology
Clinical research activity includes advanced and locally advanced non-small cell lung cancer, small cell lung cancer, and other thoracic malignancies, with attention to molecularly defined disease such as EGFR-altered, ALK-rearranged, RET fusion-positive, and KRAS G12C-mutant tumors.
- Non-small cell lung cancer
- Small cell lung cancer
- Malignant pleural mesothelioma
- Head and neck squamous cell carcinoma
The therapeutic focus extends to treatment-resistant and perioperative lung cancer settings, alongside biomarker-driven strategies for precision oncology.
Gastroenterology and Hepatology
Research interests cover inflammatory bowel disease, cirrhosis, portal hypertension, and chronic liver disorders including non-alcoholic steatohepatitis, primary biliary cholangitis, and hepatocellular carcinoma.
- Crohn's disease
- Ulcerative colitis
- Hepatic encephalopathy
- Primary sclerosing cholangitis
Additional work includes metabolic liver disease, cholestatic pruritus, and complications of advanced hepatic dysfunction.
Breast and Gynecologic Malignancies
Clinical trial involvement includes breast cancer across hormone receptor-positive, HER2-positive, and HER2-negative subtypes, as well as endometrial cancer, ovarian cancer, and cervical cancer.
- Advanced breast cancer
- Endometrial cancer
- Ovarian cancer
- Locally advanced cervical cancer
Therapeutic themes include endocrine-based treatment, targeted oncology, and management of recurrent or metastatic disease.
Hematologic Malignancies
Investigational work spans lymphoma, multiple myeloma, and acute leukemia, with activity in relapsed, refractory, and newly diagnosed settings.
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
- Acute lymphoblastic leukemia
- Multiple myeloma
Research also includes Hodgkin lymphoma, mantle cell lymphoma, and other aggressive or treatment-resistant hematologic cancers.
Respiratory and Systemic Inflammatory Disease
Additional clinical interests include chronic obstructive pulmonary disease, severe asthma, idiopathic pulmonary fibrosis, and immune-mediated disorders such as rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis.
- Chronic obstructive pulmonary disease
- Severe asthma
- Idiopathic pulmonary fibrosis
- Multiple sclerosis
This portfolio also includes selected studies in cardiovascular disease, atrial fibrillation, and metabolic conditions linked to long-term organ dysfunction.
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