Xavier Miquel B. A.
- Country
- Spain
- Department
- 6002: Servicio de Inmunología y Genética Molecular
Research Overview
Data & Insights
Has run more than one trial at 0 of 11 partner sites.
Specializations
Advanced Solid Tumor Oncology
Investigates therapeutic strategies for metastatic breast cancer and other high‑risk solid malignancies.
- Targeted therapy for HER2‑negative breast cancer
- Precision medicine in non‑small cell lung cancer
- Combination immunotherapy for renal cell carcinoma
- Novel agents in advanced melanoma
- Biomarker‑driven trials in gastro‑esophageal adenocarcinoma
Research conducted at Hospital Clinic de Barcelona.
Hematologic Malignancies
Focuses on innovative treatments for multiple myeloma and related blood cancers.
- CAR‑T cell approaches for relapsed B‑cell lymphoma
- Antibody‑drug conjugates in acute myeloid leukemia
- Maintenance strategies for post‑transplant myeloma
- Targeted inhibition in chronic lymphocytic leukemia
- Novel immunomodulators for mantle cell lymphoma
Clinical investigations are coordinated through the Servicio de Inmunología y Genética Molecular.
Immunology & Autoimmune Disorders
Develops therapeutic options for systemic autoimmune diseases.
- Biologic modulation in psoriatic arthritis
- Targeted therapy for systemic lupus erythematosus
- Immune tolerance in idiopathic inflammatory myopathy
- Novel agents for immune thrombocytopenia
- Precision treatments for ANCA‑associated vasculitis
Studies leverage the department’s expertise in molecular immunogenetics.
Infectious Diseases & Mycobacterial Infections
Explores therapies for challenging infections such as nontuberculous mycobacterial lung disease.
- Antimicrobial regimens for Mycobacterium avium complex
- Adjunctive strategies in severe COVID‑19
- Therapeutic vaccines for chronic hepatitis B
- Novel agents against Candida bloodstream infections
- Immune‑based therapies for viral reactivation post‑transplant
Research integrates clinical microbiology with host immune profiling.
Cardiovascular & Metabolic Medicine
Targets disease pathways in atherosclerotic cardiovascular disease and related metabolic disorders.
- IL‑6 inhibition for reduction of cardiovascular events
- SGLT2‑inhibitor combination therapy in heart failure with preserved ejection fraction
- Risk stratification in atrial fibrillation
- Therapeutic approaches for non‑alcoholic steatohepatitis
- Management of hypertriglyceridemia in high‑risk patients
Clinical programs are supported by the center’s cardiometabolic research platform.
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