person

Wolf A. L.

Country
Germany
Department
Klinik für Augenheilkunde

Research Overview

Data & Insights

medical_services
Primary Speciality
Main therapeutic area

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Return Partnerships
Recurring site collaborations
0
Sites with multiple studies

Has run more than one trial at 0 of 16 partner sites.

Specializations

Atrial Fibrillation Therapeutics

Focus on novel oral anticoagulants and rhythm‑control strategies for atrial fibrillation to reduce stroke and systemic embolism.

  • Asundexian comparative efficacy
  • Colchicine post‑electrocardioversion
  • Recurrence monitoring after electrical cardioversion

Clinical investigations are conducted at the Medical Center – University Of Freiburg.

Acute Myocardial Infarction Management

Evaluation of rapid‑acting agents for self‑administration during symptom onset of acute myocardial infarction.

  • Selatogrel self‑administration
  • Recurrent AMI risk reduction

The study integrates emergency response protocols within the same research site.

Aortic Stenosis and Valve Replacement

Assessment of pharmacologic modulation, specifically beta‑blocker therapy, in patients undergoing transcatheter aortic valve replacement.

  • Beta‑blocker impact on TAVR outcomes
  • Hemodynamic optimization post‑procedure

Collaboration with cardiac surgery units supports comprehensive data collection.

Lipoprotein(a) and Atherosclerotic Cardiovascular Disease

Investigation of targeted RNA‑based therapies to lower lipoprotein(a) levels in individuals with atherosclerotic cardiovascular disease.

  • Olpasiran efficacy on CHD death
  • Lp(a) reduction and event risk

Outcomes are measured against standard of care within the University Of Freiburg cohort.

Integrated Cardiovascular Risk Prevention

Broad exploration of antithrombotic and anti‑inflammatory interventions to mitigate overall cardiovascular disease burden.

  • Antithrombotic strategy comparison
  • Inflammation modulation with colchicine

The investigator leverages the interdisciplinary environment of the ophthalmology clinic to incorporate vascular imaging expertise.

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