Winfried A.
- Country
- Germany
- Department
- Medizinische Klinik II Onkologisches Zentrum
Research Overview
- A Phase I Study of TK-6302 in Patients with Advanced PRAME-Positive Solid Tumors Harboring the HLA-A*02:01 Allele
- Phase 1/2a Study of REGN10597 Alone or with Cemiplimab in Patients with Advanced Solid Tumours, Melanoma, or Clear-Cell Renal Cell Carcinoma
- Phase III Randomized Trial of De-escalated MATRix Induction Therapy in Newly Diagnosed Primary CNS Lymphoma: Methotrexate, Cytarabine, Thiotepa, and Rituximab
Data & Insights
Has run more than one trial at 8 of 67 partner sites.
Specializations
Oncology Focus
The investigator specializes in treating solid organ tumors through innovative cellular therapy approaches. Their research encompasses chimeric antigen receptor T cell (CAR-T) treatments, particularly focusing on claudin 6 targeted therapies.
- Advanced Cell Therapies
- RNA-based Vaccine Development
- Immunotherapy Applications
Their work integrates novel therapeutic combinations including cell-based treatments and RNA vaccines.
Neuro-Oncology
The investigator has extensive experience in treating primary central nervous system lymphoma, with particular emphasis on diffuse large B-cell lymphoma (DLBCL) of the central nervous system.
- CNS Lymphoma Treatment
- Combination Chemotherapy Protocols
- Stem Cell Transplantation
Their research involves optimizing treatment protocols combining Methotrexate, Ara-C, Thiotepa, and Rituximab with high-dose therapy approaches.
Therapeutic Innovation
The investigator develops treatment strategies for rare and aggressive cancers, focusing on autologous stem cell transplantation and innovative drug combinations.
- Protocol Optimization
- Treatment De-escalation Strategies
- Novel Therapeutic Combinations
Their work aims to enhance treatment efficacy while optimizing therapeutic protocols for improved patient outcomes.
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