Wieslaw C.
- Country
- Poland
- Department
- Klinika Psychiatrii Dorosłych
Research Overview
- Phase 2b Randomized, Double-Blind, Placebo-Controlled Trial Evaluating Mebufotenin (GH001) Efficacy and Safety in Treatment-Resistant Depression Patients
- Efficacy and Tolerability of BH-200 (Nelivaptan) in V1b-High Outpatients with Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Phase II Study
- Evaluation of the Efficacy and Safety of Lysergide (MM120) in Adults with Generalized Anxiety Disorder: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 45 of 129 partner sites.
Specializations
Psychiatry and Mood Disorders
Clinical trial activity in adult psychiatry centers on conditions such as refractory schizophrenia, treatment-resistant depression, bipolar disorder, and major depressive disorder, with additional interest in complex neuropsychiatric syndromes.
- Refractory schizophrenia
- Treatment-resistant depression
- Bipolar-I mania
- Major depressive disorder
Work in this area also includes cognitive disorder, psychosis associated with Alzheimer’s disease, and schizophrenia with persistent symptoms.
Hematologic Malignancies
A major therapeutic focus is hematology-oncology, especially acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, and diverse lymphomas including aggressive and relapsed or refractory subtypes.
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Classical Hodgkin lymphoma
- Multiple myeloma
Additional interest extends to chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, and myelofibrosis.
Solid Tumors and Precision Oncology
Research involvement spans non-small cell lung cancer, small cell lung cancer, breast cancer, melanoma, and head and neck squamous cell carcinoma, with emphasis on advanced and metastatic disease.
- Non-small cell lung cancer
- Breast cancer
- Melanoma
- Head and neck squamous cell carcinoma
Therapeutic interests also include ovarian cancer, renal cell carcinoma, hepatocellular carcinoma, and biomarker-defined targets such as EGFR, ALK, and KRAS alterations.
Cardiovascular and Metabolic Disease
Clinical research activity includes atherosclerotic cardiovascular disease, atrial fibrillation, myocardial infarction, heart failure, and hypertension, alongside broader cardiometabolic risk reduction.
- Atherosclerotic cardiovascular disease
- Heart failure
- Atrial fibrillation
- Hypertension
Additional areas include hyperlipidemia, familial hypercholesterolemia, obesity, and type 2 diabetes.
Immune, Neurologic, and Rare Disorders
The investigator is also involved in trials addressing generalized myasthenia gravis, multiple sclerosis, autoimmune hemolytic anemia, systemic lupus erythematosus, and vasculitis.
- Generalized myasthenia gravis
- Multiple sclerosis
- Autoimmune hemolytic anemia
- Systemic lupus erythematosus
Further therapeutic interests include amyloidosis, pulmonary arterial hypertension, interstitial lung disease, asthma, and selected rare genetic disorders.
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