WELNIARZ A.
- Country
- France
- Department
- Service de Neuro-Urologie
Research Overview
Data & Insights
Has run more than one trial at 0 of 8 partner sites.
Specializations
Neuro‑Urology & Bladder Dysfunction
The investigator focuses on disorders of urinary control linked to neurological injury, including neurogenic bladder and detrusor overactivity in multiple sclerosis or spinal cord injury.
- Detrusor overactivity
- Neurogenic bladder
- Recurrent urinary tract infections
- Spinal cord injury
- Intermittent catheterisation
Research includes therapeutic strategies to reduce infection risk and improve bladder storage.
Neuromuscular & Muscular Dystrophies
Clinical activity encompasses rare muscle disorders such as Duchenne muscular dystrophy and spinal muscular atrophy, targeting disease‑modifying agents.
- Duchenne muscular dystrophy
- Spinal muscular atrophy
- Risdiplam combination therapy
- Gene‑based treatments
- Motor function preservation
Efforts aim to assess safety and functional outcomes in pediatric and adult cohorts.
Infectious Diseases & Antiviral Strategies
Work includes viral co‑infection management and novel antibody approaches for HIV‑1 and hepatitis B, as well as bacterial pneumonia interventions.
- HIV‑1 primary infection
- HBV co‑infection
- Broadly neutralising antibodies
- Community‑acquired pneumonia
- Severe bacterial pneumonia
Trials evaluate remission durability and antimicrobial stewardship.
Cerebrovascular & Stroke Prevention
Investigations address acute and secondary prevention of ischemic events, including acute ischemic stroke and high‑risk transient ischemic attack.
- Acute ischemic stroke
- High‑risk transient ischemic attack
- FXIa inhibition
- Antithrombotic therapy
- Post‑stroke pain
Focus is on reducing recurrent events and bleeding complications.
Lysosomal Storage & Metabolic Disorders
The portfolio includes rare enzyme‑deficiency diseases such as Fabry disease and Pompe disease, exploring substrate reduction and enzyme replacement enhancements.
- Fabry disease
- Pompe disease
- Enzyme replacement therapy
- Substrate reduction therapy
- Neuropathic pain management
Studies assess long‑term safety and quality‑of‑life outcomes.
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