Idris B.
- Country
- The Netherlands
- Department
- Pulmonary Medicine
Research Overview
- A Phase III Double-Blind, Placebo-Controlled Study of Adjuvant Durvalumab in Resected Stage IB-IIIA Non-Small Cell Lung Cancer with PD-L1 Expression ≥25%
- Long-term Safety and Efficacy Evaluation of Inhaled Seralutinib in Pulmonary Arterial Hypertension: An Open-label Extension Study
- Phase II Randomized Trial of BMS-986012 with Carboplatin, Etoposide, and Nivolumab in First-line Treatment of Extensive-stage Small Cell Lung Cancer
Data & Insights
Has run more than one trial at 58 of 245 partner sites.
Specializations
Pulmonary Oncology
Clinical research activity centers on non-small cell lung cancer, small cell lung cancer, and other thoracic malignancies, with interest in treatment strategies for locally advanced, resectable, and metastatic disease.
- Non-small cell lung cancer
- Small cell lung cancer
- Thoracic cancer
- Head and neck squamous cell carcinoma
- Esophageal cancer
There is also involvement in biomarker-driven oncology and immunotherapy-oriented care for advanced solid tumors.
Respiratory and Interstitial Lung Disease
The investigator is engaged in studies of chronic and progressive lung disease, including idiopathic pulmonary fibrosis, interstitial lung disease, chronic lung disease, and bronchiectasis.
- Idiopathic pulmonary fibrosis
- Interstitial lung disease
- Bronchiectasis
- Chronic lung disease
- Chronic thromboembolic pulmonary hypertension
Research also extends to pulmonary arterial hypertension and other complex respiratory conditions requiring specialized clinical management.
Onco-Hematology and Cellular Therapy
Research interests include lymphoma, multiple myeloma, acute myeloid leukemia, chronic lymphocytic leukemia, and myelodysplastic syndromes, with a strong focus on advanced hematologic malignancies.
- Diffuse large B-cell lymphoma
- Multiple myeloma
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- Myelodysplastic syndromes
There is also active involvement in CAR T-cell therapy and other cell-based treatments for relapsed or refractory blood cancers.
Autoimmune and Inflammatory Disease
The investigator contributes to trials in inflammatory bowel disease, rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, and idiopathic inflammatory myopathy.
- Crohn's disease
- Ulcerative colitis
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Systemic sclerosis
Additional interests include vasculitis, myositis, and other immune-mediated disorders affecting the lungs and systemic organs.
Cardiovascular and Thromboembolic Disease
Clinical research also spans coronary artery disease, heart failure, atrial fibrillation, hypertension, and atherosclerotic cardiovascular disease.
- Coronary artery disease
- Heart failure
- Atrial fibrillation
- Hypertension
- Thromboembolic disease
Research involvement includes stroke prevention, pulmonary hypertension, and other cardiovascular conditions with significant therapeutic need.
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