Vlad R.
- Country
- France
- Department
- Hépato gastro entérologie
Research Overview
- N1T-MC-MALO: A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes (SYNERGY-Outcomes); N1T-MC-TZ01 Tirzepatide in participants with high-risk MASLD; N1T-MC-RT01 Retatrutide in participants with high-risk MASLD
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa in Adults with Biopsy‑Confirmed F2–F3 Metabolic Dysfunction‑Associated Steatohepatitis
- Phase 3 Randomized Double‑Blind Placebo‑Controlled Study of Efimosfermin Alfa Safety and Tolerability in Adults with F2‑F3 Metabolic Dysfunction‑Associated Steatohepatitis
Data & Insights
Has run more than one trial at 201 of 332 partner sites.
Specializations
Liver Metabolic Disorders
This investigator specializes in treating non-alcoholic steatohepatitis (NASH) and metabolic dysfunction-associated steatohepatitis (MASH), with particular focus on advancing therapeutic approaches for patients with varying stages of liver fibrosis.
- NASH/MASH with Fibrosis Treatment
- Cirrhosis Management
- Metabolic Liver Disease Progression
Their work encompasses both compensated and non-cirrhotic stages of these conditions.
Autoimmune Liver Diseases
The investigator focuses on therapeutic interventions for primary biliary cholangitis (PBC), exploring novel treatment combinations and long-term disease management strategies.
- PBC Treatment Development
- Cholestasis Management
- Biochemical Disease Markers
Their research includes evaluation of various therapeutic compounds for PBC patients with inadequate response to conventional treatments.
Viral Hepatology
Expertise in treating chronic hepatitis B infection, with emphasis on developing functional cure strategies and innovative therapeutic approaches.
- HBV Treatment Optimization
- Antiviral Therapy
- Immune Response Modulation
The investigator explores novel treatment paradigms for chronic viral hepatitis management.
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