Viktorija K.
- Country
- Latvia
- Department
- Rare Neurological Disease Department
Research Overview
- Efficacy and Safety Evaluation of DNTH103 in Adults with Chronic Inflammatory Demyelinating Polyneuropathy: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial
- Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial of Masitinib and Riluzole in Amyotrophic Lateral Sclerosis Patients
- Phase 3 Randomized Double-Blind Study of Empasiprubart vs. Human Normal Immunoglobulin (IV) in Adults with Multifocal Motor Neuropathy
Data & Insights
Has run more than one trial at 24 of 123 partner sites.
Specializations
Rare Neurological Diseases
Clinical research activity in rare neurological disease includes amyotrophic lateral sclerosis, multiple sclerosis, focal-onset seizures, primary generalized tonic-clonic seizures, multifocal motor neuropathy, and chronic inflammatory demyelinating polyneuropathy.
- Amyotrophic lateral sclerosis
- Multiple sclerosis
- Focal-onset seizures
- Multifocal motor neuropathy
Additional interests extend to relapsing multiple sclerosis, secondary progressive multiple sclerosis, and broader nervous system diseases.
Immune-Mediated Gastrointestinal Disease
The investigator is involved in studies of Crohn's disease and ulcerative colitis, with attention to both moderately to severely active inflammatory bowel disease and longer-term disease control.
- Crohn's disease
- Ulcerative colitis
- Moderately to severely active Crohn's disease
- Moderately to severely active ulcerative colitis
Related therapeutic interest also includes systemic lupus erythematosus and other immune-mediated inflammatory disorders.
Cardiovascular and Thrombotic Disorders
Research involvement spans atherosclerotic cardiovascular disease, atrial fibrillation, ischemic stroke, venous thromboembolism, heart failure, and hypercholesterolemia.
- Atherosclerotic cardiovascular disease
- Atrial fibrillation
- Ischemic stroke
- Venous thromboembolism
Therapeutic focus also includes major adverse cardiovascular events, hypertriglyceridemia, and prevention of recurrent vascular complications.
Respiratory and Pulmonary Vascular Disease
Clinical interests include chronic obstructive pulmonary disease, asthma, bronchiectasis, community-acquired pneumonia, pulmonary arterial hypertension, and pulmonary hypertension associated with interstitial lung disease.
- Chronic obstructive pulmonary disease
- Asthma
- Bronchiectasis
- Pulmonary arterial hypertension
Additional attention is directed toward severe respiratory infection and inflammatory airway disease.
Ophthalmology, Renal, and Metabolic Conditions
The research portfolio also includes diabetic macular edema, neovascular age-related macular degeneration, geographic atrophy, diabetic retinopathy, immunoglobulin A nephropathy, chronic kidney disease, and type 2 diabetes.
- Diabetic macular edema
- Neovascular age-related macular degeneration
- Immunoglobulin A nephropathy
- Type 2 diabetes
Related therapeutic areas include obesity, classic congenital adrenal hyperplasia, and severe hypertriglyceridemia.
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