Viera H.
- Country
- Slovakia
- Department
- #5502: UNB Ružinov, Neurologická klinika
Research Overview
- Efficacy and Safety of Remibrutinib in Patients with Secondary Progressive Multiple Sclerosis: A Phase III, Randomized, Double-Blind, Placebo-Controlled Study
- Evaluation of Ocrelizumab Efficacy and Safety in Multiple Sclerosis Patients from a Prior Phase IIIb/IV Trial
- Evaluation of Ofatumumab Efficacy and Patient-Reported Outcomes in Relapsing Multiple Sclerosis Patients Transitioning from Fumarate-Based Therapies or Fingolimod
Data & Insights
Has run more than one trial at 234 of 521 partner sites.
Specializations
Multiple Sclerosis and Neuroimmunology
Clinical research activity is centered on multiple sclerosis, including relapsing multiple sclerosis, primary progressive multiple sclerosis, and secondary progressive multiple sclerosis. The portfolio also includes interest in broader nervous system diseases and inflammatory mechanisms affecting neurological function.
- Relapsing multiple sclerosis
- Primary progressive multiple sclerosis
- Secondary progressive multiple sclerosis
- Lower limb spasticity
- Refractory status epilepticus
Therapeutic involvement extends to disease-modifying strategies, relapse prevention, and long-term control of neurological disability.
Neurodegenerative and Cognitive Disorders
Research interests include conditions affecting cognition and movement, with work spanning Alzheimer’s disease-related syndromes, Parkinson's disease, and mild cognitive impairment. The clinical scope also covers neuropsychiatric manifestations linked to degenerative brain disease.
- Mild cognitive impairment
- Alzheimer’s disease dementia
- Parkinson's disease
- Psychosis associated with Alzheimer’s disease
- Agitation in Alzheimer’s disease dementia
The therapeutic focus includes symptom control, functional preservation, and interventions aimed at slowing neurological decline.
Ophthalmology and Retinal Disease
There is strong involvement in eye disease research, especially neovascular age-related macular degeneration, diabetic macular edema, and macular edema secondary to retinal vein occlusion. Additional interest is seen in thyroid eye disease and diabetic retinal complications.
- Neovascular age-related macular degeneration
- Diabetic macular edema
- Macular edema secondary to retinal vein occlusion
- Thyroid eye disease
- Diabetic retinopathy
Therapeutic activity is directed toward visual outcomes, retinal preservation, and treatment of chronic retinal vascular disease.
Cardiometabolic, Renal, and Inflammatory Disease
Clinical trial involvement also covers heart failure, atherosclerotic cardiovascular disease, hypertension, chronic kidney disease, and immunoglobulin A nephropathy. Metabolic and inflammatory conditions such as obesity and non-alcoholic steatohepatitis are part of this research landscape.
- Heart failure
- Atherosclerotic cardiovascular disease
- Chronic kidney disease
- Immunoglobulin A nephropathy
- Non-alcoholic steatohepatitis
The therapeutic emphasis includes cardioprotection, renal preservation, and management of systemic inflammatory burden.
Oncology, Autoimmune, and Rare Disease Therapies
Additional research spans non-small cell lung cancer, multiple myeloma, chronic myeloid leukemia, and rare immune-mediated or genetic disorders such as bullous pemphigoid, atypical hemolytic uremic syndrome, and Niemann-Pick disease type C. Dermatologic and hair-loss conditions, including alopecia areata and hidradenitis suppurativa, are also represented.
- Non-small cell lung cancer
- Multiple myeloma
- Bullous pemphigoid
- Alopecia areata
- Atypical hemolytic uremic syndrome
Therapeutic interest covers immune modulation, targeted antineoplastic treatment, and interventions for rare systemic disorders.
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