Vicente C. B.
- Country
- Spain
- Department
- Medical Oncology
Research Overview
- Evaluation of Safety and Efficacy of Debio 0123 and Sacituzumab Govitecan in Advanced/Metastatic Triple-Negative or HR+/HER2- Breast Cancer
- Evaluation of Minimal Residual Disease Monitoring via ctDNA in HR-Positive/HER2-Negative Early Breast Cancer Using Abemaciclib, Inavolisib, and Giredestrant
- CAMBRIA-2: A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next Generation, Oral Selective Estrogen Receptor Degrader) vs Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) as Adjuvant Treatment for Patients With ER+/HER2- Early Breast Cancer and an Intermediate-High or High Risk of Recurrence Who Have Completed Definitive Locoregional Treatment and Have No Evidence of Disease
Data & Insights
Has run more than one trial at 32 of 256 partner sites.
Specializations
Breast cancer and HER2-directed therapy
Clinical research activity is strongly centered on early breast cancer, advanced breast cancer, and metastatic breast cancer, with particular interest in HER2-positive, HER2-low, HR-positive, and triple-negative breast cancer. The investigator is involved in studies of treatment intensification, endocrine-based strategies, and post-neoadjuvant approaches across disease settings.
- HER2-positive breast cancer
- HR-positive/HER2-negative breast cancer
- Triple-negative breast cancer
- Brain metastases in breast cancer
- Early-stage breast cancer
Areas of interest include antibody-drug conjugates, CDK4/6 inhibition, PI3K-targeted therapy, endocrine therapy, and immune checkpoint inhibition in breast oncology.
Thoracic oncology and lung cancer
The investigator is active in non-small cell lung cancer and small cell lung cancer research, including locally advanced, metastatic, and brain-metastatic disease. The therapeutic focus includes systemic treatment strategies for patients with advanced thoracic malignancies and disease control after initial therapy.
- Non-small cell lung cancer
- Small cell lung cancer
- Brain metastases from thoracic tumors
- Metastatic solid tumors
Research involvement also extends to immunotherapy combinations and targeted approaches in advanced lung cancer.
Hematologic malignancies
Clinical trial activity includes multiple blood cancer entities, especially diffuse large B-cell lymphoma, chronic lymphocytic leukemia, follicular lymphoma, acute myeloid leukemia, and multiple myeloma. The investigator’s work spans both untreated and relapsed disease settings.
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
- Follicular lymphoma
- Acute myeloid leukemia
- Multiple myeloma
Therapeutic interests include bispecific antibodies, BCL2 inhibition, and antibody-based regimens in lymphoma and leukemia.
Bladder cancer and uro-oncology
The investigator is involved in studies of non-muscle invasive bladder cancer and muscle-invasive bladder cancer, with attention to bladder-preserving treatment and recurrence prevention. Research also covers advanced urothelial malignancy and related metastatic disease.
- Non-muscle invasive bladder cancer
- Muscle-invasive bladder cancer
- Urothelial carcinoma
- Urinary bladder neoplasms
Clinical interest includes immunotherapy and bladder preservation strategies in uro-oncology.
Respiratory, inflammatory, and cardiometabolic disease
Beyond oncology, the investigator participates in research on severe asthma, chronic obstructive pulmonary disease, atopic dermatitis, chronic spontaneous urticaria, and chronic inducible urticaria. Additional activity includes atherosclerotic cardiovascular disease, hypertension, elevated lipoprotein(a), and metabolic dysfunction-associated steatohepatitis.
- Severe asthma
- Chronic obstructive pulmonary disease
- Chronic spontaneous urticaria
- Atopic dermatitis
- Metabolic dysfunction-associated steatohepatitis
Therapeutic interests also include respiratory biologics, cardiovascular risk reduction, and fibrotic liver disease.
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