Vasil B.
- Country
- Bulgaria
- Department
- Department of Internal Medicine
Research Overview
- Efficacy and Safety of Linaprazan Glurate versus Lansoprazole for Maintenance of Healing in Patients with Healed Erosive Esophagitis Due to Gastroesophageal Reflux Disease
- Evaluation of Linaprazan Glurate Versus Lansoprazole in Healing Erosive Esophagitis Due to Gastroesophageal Reflux Disease: A Phase 3 Randomized Controlled Trial
- ADVANCE: A Phase III Multi-Centre, Randomised, Double-Blind, Double-Dummy Clinical Trial Comparing Essentiale® Liquid vs. Capsules for MASLD/MASH, Alcoholic Liver Disease, and Chronic Viral Hepatitis B
Data & Insights
Has run more than one trial at 64 of 85 partner sites.
Specializations
Cardiovascular and cerebrovascular disease
Clinical research activity includes prevention of recurrent ischemic stroke after acute non-cardioembolic events and high-risk transient ischemic attack, alongside studies in atherosclerotic cardiovascular disease, hyperlipidemia, and hypertriglyceridemia.
- Secondary stroke prevention
- Atherosclerosis
- Lipid disorders
Work in this area also extends to cardiovascular risk reduction in patients with established vascular disease.
Heart failure, kidney disease, and hypertension
The investigator is involved in studies addressing heart failure with comorbid renal impairment, chronic kidney disease, and hypertension, including outcomes linked to cardiovascular death and worsening renal function.
- Heart failure events
- Renal protection
- Blood pressure control
This therapeutic focus includes patients with combined cardiometabolic and renal risk.
Metabolic and endocrine disorders
Research interests cover type 2 diabetes, obesity, and broader metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis, reflecting involvement in cardiometabolic disease management.
- Type 2 diabetes
- Obesity
- Fatty liver disease
Additional activity includes treatment areas linked to metabolic risk and cardiovascular comorbidity.
Respiratory and allergic airway disease
Clinical trial involvement includes severe asthma and chronic obstructive pulmonary disease, with attention to exacerbation control and persistent airway inflammation in patients with inadequate symptom control.
- Severe asthma
- COPD
- Exacerbation prevention
These studies address chronic respiratory disease burden in adults with ongoing exacerbation risk.
Gastrointestinal, hepatic, and infectious disease care
Research activity also spans erosive esophagitis due to gastroesophageal reflux disease, alcoholic liver disease, chronic viral hepatitis B, and pediatric complicated urinary tract infection including acute pyelonephritis.
- Erosive esophagitis
- Chronic liver disease
- Urinary tract infection
These areas reflect involvement across digestive, hepatic, and antimicrobial therapeutic domains.
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