Vanesa O. C.
- Country
- Spain
- Department
- Oncology
Research Overview
- Phase III Trial of BNT327 plus Combination Chemotherapy versus Placebo plus Chemotherapy in Patients with Previously Untreated Metastatic or Locally Recurrent Triple-Negative Breast Cancer
- A Phase I Study of SIE-1 in Post-menopausal Women with Hormone Receptor-positive Early Breast Cancer
- Efficacy and Safety of RLY-2608 Plus Fulvestrant Versus Capivasertib Plus Fulvestrant in PIK3CA-Mutant HR+/HER2- Advanced Breast Cancer
Data & Insights
Has run more than one trial at 32 of 192 partner sites.
Specializations
Breast Cancer and Gynecologic Oncology
Clinical research activity centers on hormone receptor-positive breast cancer, HER2-negative and HER2-positive breast cancer, triple-negative breast cancer, and other advanced solid tumors, with additional interest in ovarian cancer and cervical cancer.
- Metastatic breast cancer
- Early breast cancer
- Ovarian cancer
- Solid tumors
Work in this area includes therapies linked to endocrine treatment, HER2-targeted therapy, and antibody-drug conjugates, reflecting a strong focus on precision approaches in oncology.
Neurodegenerative Disease
Another major therapeutic domain is Alzheimer’s disease, including preclinical Alzheimer’s disease, early Alzheimer’s disease, mild cognitive impairment, and mild dementia, alongside studies in Parkinson’s disease and related movement disorders.
- Alzheimer’s disease
- Parkinson’s disease
- Multiple system atrophy
- Progressive supranuclear palsy
The therapeutic landscape also includes agents directed at amyloid, tau, and cognitive decline, as well as interventions relevant to motor symptoms and functional impairment.
Retinal and Ophthalmic Disorders
Clinical involvement extends to retinal disease and vision-threatening conditions such as diabetic macular edema, diabetic retinopathy, neovascular age-related macular degeneration, and geographic atrophy.
- Diabetic macular edema
- Age-related macular degeneration
- Geographic atrophy
- Retinal vein occlusion
Research interests in this field align with intravitreal therapy, visual acuity preservation, and treatments aimed at slowing retinal degeneration.
Neuromuscular and Autoimmune Disease
Additional clinical activity includes generalized myasthenia gravis, with attention to disorders affecting neuromuscular transmission and immune-mediated disease control.
- Generalized myasthenia gravis
- Neuromuscular disorders
- Autoimmune disease
This area reflects therapeutic interest in immune modulation and symptom control for chronic neurologic disease.
Vaccines and Maternal-Infant Health
Research also includes meningococcal vaccination, respiratory syncytial virus prevention, and care relevant to pregnancy and fertility.
- Meningococcal immunization
- RSV prevention
- Pregnancy-related care
- Infertility
The therapeutic scope in this domain spans preventive medicine and reproductive health support.
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