Valérien R.
- Country
- France
- Department
- IUCT oncopole
Research Overview
Data & Insights
Has run more than one trial at 0 of 6 partner sites.
Specializations
Targeted Oncology in Solid Tumors
Focus on molecularly defined solid malignancies treated with innovative agents.
- MTAP‑deleted cancers
- Hormone‑receptor‑positive HER2‑negative breast cancer
- HER2‑positive gastric and gastro‑esophageal adenocarcinoma
- FGFR‑altered urothelial carcinoma
Integrates biomarker‑driven patient selection across multiple tumor types.
Hematologic Malignancies and Myelodysplasia
Investigates acute leukemias and myelodysplastic syndromes with novel therapeutic strategies.
- Acute myeloid leukemia
- Acute lymphoblastic leukemia
- Myelodysplastic syndrome with IDH1/2 mutations
- Chronic lymphocytic leukemia
Emphasizes risk‑adapted approaches for high‑risk hematologic diseases.
Autoimmune and Inflammatory Disorders
Addresses systemic immune‑mediated diseases using targeted immunomodulation.
- ANCA‑associated vasculitis
- Systemic lupus erythematosus with nephritis
- Psoriatic arthritis
- Idiopathic pulmonary fibrosis
Targets pathogenic pathways to modify disease progression.
Cardiovascular and Metabolic Medicine
Targets acute coronary events and chronic cardiovascular risk in metabolic contexts.
- Acute myocardial infarction
- Atherosclerotic cardiovascular disease
- Heart failure with reduced ejection fraction
- Type 2 diabetes mellitus
Combines anti‑inflammatory and lipid‑lowering strategies to improve outcomes.
Rare Genetic and Metabolic Syndromes
Explores therapeutic options for uncommon hereditary and protein‑misfolding disorders.
- Transthyretin amyloid cardiomyopathy
- VEXAS syndrome
- Neuroendocrine tumor of gastro‑enteric origin
- Alport syndrome
Leverages disease‑specific molecular insights to guide treatment selection.
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