V. V.
- Country
- Belgium
- Department
- Hematology
Research Overview
- Randomized European Trial of Autologous Transplantation with Rituximab, Ibrutinib, and Ara-C Induction in Generalized Mantle Cell Lymphoma
- Phase 2 Evaluation of Golcadomide (CC-99282) in Relapsed/Refractory Primary and Secondary Central Nervous System Large B-Cell Lymphoma
- HOVON 152 DLBCL. A phase II study evaluating the effect of DA-EPOCH-R induction followed by nivolumab consolidation in patients with newly diagnosed high grade B cell lymphoma (HGBL) with MYC and BCL2 and/or BCL6 rearrangements
Data & Insights
Has run more than one trial at 18 of 152 partner sites.
Specializations
Hematologic Malignancies
Specializes in hematologic malignancies, targeting diseases that arise from malignant transformation of hematopoietic cells.
- Acute Myeloid Leukemia
- Acute Lymphoblastic Leukemia
- Chronic Myeloid Leukemia
- Chronic Lymphocytic Leukemia
- Multiple Myeloma
- Diffuse Large B‑Cell Lymphoma
- Hodgkin Lymphoma
Clinical programs aim to integrate novel agents into standard regimens.
Solid Tumor Oncology
Focuses on aggressive solid tumors, emphasizing molecularly defined subtypes across diverse organ sites.
- Breast Cancer
- Non‑Small Cell Lung Cancer
- Ovarian Cancer
- Colorectal Cancer
- Pancreatic Ductal Adenocarcinoma
- Renal Cell Carcinoma
- Melanoma
Efforts include biomarker‑driven strategies for therapy selection.
Autoimmune & Inflammatory Diseases
Investigates immune‑mediated disorders with systemic involvement affecting skin, joints, and internal organs.
- Lupus Nephritis
- Rheumatoid Arthritis
- Inflammatory Bowel Disease
- Psoriasis
- Systemic Sclerosis
- Myasthenia Gravis
- Ulcerative Colitis
Therapeutic work seeks to modulate dysregulated immune pathways.
Rare Genetic & Metabolic Disorders
Dedicated to inherited metabolic disorders and neuromuscular diseases that affect multiple organ systems.
- Pompe Disease
- Duchenne Muscular Dystrophy
- Fabry Disease
- Transthyretin Amyloidosis
- Alpha‑1 Antitrypsin Deficiency
- Glycogen Storage Disease Type II
- Autosomal Dominant Polycystic Kidney Disease
Research includes enzyme replacement and gene‑targeted approaches.
Cardiopulmonary Diseases
Addresses chronic cardiopulmonary diseases that contribute to high morbidity and mortality.
- Chronic Obstructive Pulmonary Disease
- Atherosclerotic Cardiovascular Disease
- Pulmonary Arterial Hypertension
- Heart Failure
- Atrial Fibrillation
- Hypertension
- Obesity
Studies evaluate disease‑modifying therapies for long‑term outcomes.
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