Ulrik O.
- Country
- Denmark
- Department
- Department of Hematology
Research Overview
- ALLTogether1 - A Treatment Study Protocol of the ALLTogether Consortium for Children and Young Adults (0-45 Years of Age) with Newly Diagnosed Acute Lymphoblastic Leukaemia (ALL)
- AALL2131/EsPhALL2022, An International Pilot Study of Chemotherapy and Tyrosine Kinase Inhibitor with Blinatumomab in Patients with Newly Diagnosed Philadelphia Chromosome Positive or ABL-class Philadelphia Chromosome-Like B-cell Acute Lymphoblastic Leukemia
Data & Insights
Has run more than one trial at 35 of 151 partner sites.
Specializations
Haematologic Malignancies
Clinical research in Department of Hematology is centred on acute myeloid leukemia, acute lymphoblastic leukemia, chronic lymphocytic leukemia, and a broad spectrum of lymphomas and myeloma. The investigator is also involved in studies addressing relapsed and refractory blood cancers, including aggressive and high-risk subtypes.
- Acute leukemia
- Non-Hodgkin lymphoma
- Multiple myeloma
- Myelodysplastic syndromes
Research activity extends to stem cell transplantation, CAR T-cell therapy, and targeted approaches for molecularly defined haematologic disease.
Solid Tumours and Molecular Oncology
The investigator has a strong therapeutic focus on advanced solid tumours, with activity across breast cancer, lung cancer, colorectal cancer, ovarian cancer, prostate cancer, and urothelial carcinoma. Trial involvement also includes cancers defined by actionable molecular alterations and metastatic disease.
- Non-small cell lung cancer
- Triple-negative breast cancer
- Metastatic colorectal cancer
- Advanced prostate cancer
Interest also covers precision oncology in tumours with HER2, KRAS, MET, RET, and MTAP alterations.
Cardiovascular Medicine
Clinical trial involvement includes myocardial infarction, heart failure, atrial fibrillation, cardiac arrest, pulmonary embolism, and atherosclerotic cardiovascular disease. The investigator also participates in research on post-procedural and perioperative cardiovascular care.
- Acute coronary syndromes
- Pulmonary arterial hypertension
- Cardiogenic shock
- Coronary artery bypass grafting
Additional work spans thromboembolic disease, valvular heart disease, and secondary prevention strategies in high-risk cardiovascular populations.
Neurology and Autoimmune Disease
The investigator is engaged in studies of multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, stroke, and migraine. Research also includes immune-mediated disorders affecting the central and peripheral nervous systems.
- Relapsing multiple sclerosis
- Generalized myasthenia gravis
- Idiopathic intracranial hypertension
- Neuropathic pain
Therapeutic interests extend to autoimmune vasculitis, systemic lupus erythematosus, and Sjögren’s disease.
Paediatrics, Rare Disease, and Transplant-Related Care
Research activity includes paediatric oncology, rare genetic disorders, muscular dystrophies, cystic fibrosis, and metabolic disease. The investigator is also involved in haemophilia, renal disease, and transplant-associated complications.
- Acute lymphoblastic leukaemia in children
- Neuroblastoma
- Spinal muscular atrophy
- Kidney transplant-related disorders
Other areas include primary immunodeficiency, amyloidosis, and inherited retinal and neuromuscular diseases.
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