Trine J. N.
- Country
- Denmark
- Department
- Department of Oncology
Research Overview
- Phase 1 Dose Escalation and Cohort Expansion Study of Anti-PD-1 Monoclonal Antibody TSR-042 in Advanced Solid Tumors
- Phase 3 Study of LY4170156 (Sofetabart Mipitecan) ± Bevacizumab versus standard chemotherapy in platinum‑resistant and platinum‑sensitive ovarian cancer
- Phase 3 Randomized Study of Rinatabart Sesutecan + Bevacizumab vs Bevacizumab in Recurrent Platinum‑Sensitive Ovarian Cancer after Second‑Line Platinum Doublet
Data & Insights
Has run more than one trial at 153 of 311 partner sites.
Specializations
Hematologic Malignancies
The investigator concentrates on blood‑derived cancers, including Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, chronic lymphocytic leukemia, and various forms of lymphoma and myeloma.
- Acute Myeloid Leukemia
- Acute Lymphoblastic Leukemia
- Chronic Lymphocytic Leukemia
- Diffuse Large B‑Cell Lymphoma
- Multiple Myeloma
Research aims to integrate targeted agents and immunotherapies within established regimens for these diseases.
Solid Tumor Oncology
Work in this area spans aggressive and advanced non‑small cell lung cancer, breast cancer, colorectal cancer, prostate cancer, and rare solid malignancies such as sarcoma and urothelial carcinoma.
- Non‑Small Cell Lung Cancer
- Breast Cancer
- Colorectal Cancer
- Prostate Cancer
- Urothelial Carcinoma
Efforts focus on molecularly defined subgroups, including KRAS‑mutated and HER2‑positive tumors.
Cardiovascular Medicine
In cardiovascular research the focus includes acute coronary events such as ST‑elevation myocardial infarction, chronic conditions like heart failure with reduced ejection fraction, and atherosclerotic disease management.
- ST‑Elevation Myocardial Infarction
- Heart Failure with Reduced Ejection Fraction
- Atherosclerotic Cardiovascular Disease
- Coronary Artery Disease
- Cardiogenic Shock
Investigations address novel anti‑inflammatory and antithrombotic strategies to improve outcomes.
Neuro‑degenerative and Neurological Disorders
Key interests include neurodegeneration and cerebrovascular disease, notably Alzheimer’s disease, ischemic stroke, and demyelinating conditions such as multiple sclerosis.
- Alzheimer’s Disease
- Ischemic Stroke
- Multiple Sclerosis
- Epilepsy
- Peripheral Neuropathy
Therapeutic development targets amyloid pathways, neuroinflammation, and neuro‑repair mechanisms.
Rare Genetic and Metabolic Disorders
The investigator also engages in studies of inherited and metabolic conditions such as Klinefelter syndrome, achondroplasia, Fabry disease, and muscular dystrophies.
- Klinefelter Syndrome
- Achondroplasia
- Fabry Disease
- Duchenne Muscular Dystrophy
- Cystic Fibrosis
Research emphasizes genotype‑guided therapies and disease‑modifying interventions.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.