Monika G.
- Country
- Germany
- Department
- 049037
Research Overview
- Phase II Neoadjuvant Evaluation of Capivasertib and Fulvestrant Versus Fulvestrant in Primary High-Risk Lobular Breast Cancer
- Evaluation of Elacestrant and Olaparib in Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer with gBRCA1/2 Mutations
- Phase 3 Randomized Study of Elacestrant Versus Standard Endocrine Therapy in Node-Positive, ER-Positive, HER2-Negative Early Breast Cancer with High Recurrence Risk
Data & Insights
Has run more than one trial at 21 of 249 partner sites.
Specializations
Oncology and Hematologic Malignancies
Clinical research includes a broad focus on solid tumors and blood cancers, with activity in breast cancer, ovarian cancer, hepatocellular carcinoma, colorectal cancer, renal cell carcinoma, head and neck squamous cell carcinoma, melanoma, and lung cancer. Hematologic interests extend to acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, myelofibrosis, and lymphoma.
- Breast cancer
- Acute myeloid leukemia
- Ovarian cancer
- Myelodysplastic syndromes
- Head and neck cancer
Therapeutic interest also includes advanced and recurrent disease settings, with attention to precision-matched and combination-based cancer care.
Pulmonary and Respiratory Disease
The investigator is involved in studies spanning asthma, cystic fibrosis, bronchiectasis, pulmonary arterial hypertension, interstitial lung disease, idiopathic pulmonary fibrosis, and progressive pulmonary fibrosis. Additional interest is seen in pulmonary sarcoidosis, bronchiolitis obliterans syndrome, and severe viral lung infections.
- Asthma
- Cystic fibrosis
- Pulmonary arterial hypertension
- Idiopathic pulmonary fibrosis
- Bronchiectasis
Therapeutic emphasis is directed toward chronic airway disease, fibrotic lung disease, and cardiopulmonary vascular disorders.
Autoimmune, Inflammatory, and Renal Disorders
Research activity covers systemic lupus erythematosus, lupus nephritis, Sjögren’s syndrome, primary sclerosing cholangitis, primary biliary cholangitis, Crohn’s disease, ulcerative colitis, and atopic dermatitis. Renal involvement includes IgA nephropathy, focal segmental glomerulosclerosis, chronic kidney disease, rapidly progressive glomerulonephritis, and complement-mediated glomerulopathies.
- Systemic lupus erythematosus
- Inflammatory bowel disease
- Primary sclerosing cholangitis
- IgA nephropathy
- Atopic dermatitis
Therapeutic interests also extend to immune-mediated liver disease, chronic urticaria, and other inflammatory conditions affecting multiple organ systems.
Cardiometabolic, Liver, and Kidney Medicine
Clinical trial involvement includes heart failure, myocardial infarction, coronary artery disease, pulmonary hypertension, obesity, metabolic dysfunction-associated steatohepatitis, nonalcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma. Kidney-related interests also include autosomal dominant polycystic kidney disease, proteinuria, and transplant-associated renal complications.
- Heart failure
- Metabolic liver disease
- Cirrhosis
- Autosomal dominant polycystic kidney disease
- Coronary artery disease
Therapeutic focus is centered on organ failure prevention, fibrosis-related disease, and chronic cardiometabolic risk.
Neurology, Ophthalmology, and Rare Disease Therapy
Additional research spans amyotrophic lateral sclerosis, Parkinson’s disease, Tourette syndrome, multiple sclerosis, stroke, and autoimmune encephalitis. Ophthalmic interests include diabetic macular edema, geographic atrophy, neovascular age-related macular degeneration, retinopathy of prematurity, and myopia. Rare disease work also involves hereditary angioedema, alpha-1 antitrypsin deficiency, and amyloidosis.
- Amyotrophic lateral sclerosis
- Parkinson’s disease
- Geographic atrophy
- Hereditary angioedema
- Multiple sclerosis
Therapeutic interests reflect engagement with neurodegenerative disease, vision-threatening retinal disorders, and selected rare multisystem conditions.
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