Thierry A.
- Country
- France
- Department
- Service d’oncologie médicale
Research Overview
- Phase 1 Dose Escalation and Cohort Expansion Study of Anti-PD-1 Monoclonal Antibody TSR-042 in Advanced Solid Tumors
- A Randomized, Open-label, Phase 2 study of Botensilimab (AGEN1181) as Monotherapy and in Combination with Balstilimab (AGEN2034) or Investigator’s Choice Standard of Care (Regorafenib or Trifluridine and Tipiracil) for the Treatment of Refractory Metastatic Colorectal Cancer
- Phase 1 Evaluation of NDI-219216 in Advanced Solid Tumors with/without Microsatellite Instability and Deficient Mismatch Repair
Data & Insights
Has run more than one trial at 298 of 548 partner sites.
Specializations
Colorectal Cancer Studies
The investigator specializes in treating various forms of colorectal cancer, with particular emphasis on advanced and metastatic cases. Their research encompasses both early-stage colon cancer and metastatic colorectal cancer (mCRC).
- MSI-H/dMMR colorectal cancer treatments
- BRAF V600E-mutant therapies
- KRAS/NRAS wild-type treatments
- Circulating tumor DNA analysis
The investigator works with novel therapeutic combinations including immunotherapy and targeted treatments for various molecular subtypes of colorectal cancer.
Gastric Cancer Research
The investigator focuses on treating gastric and gastroesophageal junction (GEJ) adenocarcinoma, exploring innovative therapeutic approaches for both locally advanced and metastatic disease.
- HER2-positive gastric cancer
- Perioperative treatment strategies
- CLDN18.2-positive gastric cancer
- Immunotherapy applications
Their work includes evaluation of novel treatment combinations and targeted therapies for gastric cancer patients.
Advanced Solid Tumors
The investigator conducts research on advanced solid tumors with specific genetic alterations and explores innovative therapeutic approaches across multiple cancer types.
- NTRK fusion-positive tumors
- Immunotherapy combinations
- Novel therapeutic agents
- Molecular targeting strategies
Their research includes evaluation of treatment responses in various molecular subtypes of solid tumors.
Related Investigators
Researchers in similar fields or departments
Want to know more about this investigator?
We can share extended profile information and contact details.
Is something out of date?
Tell us what needs correcting and we'll update this profile.