Thibaud L.
- Country
- France
- Department
- Centre Mémoire de Ressources et de Recherches
Research Overview
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Safety, and Tolerability of BIIB080 in Subjects with Mild Cognitive Impairment Due to Alzheimer’s Disease or Mild Alzheimer’s Disease Dementia
- Efficacy and Safety Evaluation of Latozinemab in Patients with Frontotemporal Dementia Due to Progranulin Gene Mutations: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study
- Randomized, Double-Blind, Placebo-Controlled Study on the Efficacy of Caffeine in Cognitive Decline in Early to Moderate Alzheimer's Disease
Data & Insights
Has run more than one trial at 80 of 139 partner sites.
Specializations
Neurodegenerative and Neuroimmunology
Clinical research activity includes Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, amyotrophic lateral sclerosis, and other disorders affecting cognition, movement, and central nervous system function.
- Alzheimer’s disease
- Parkinson’s disease
- Multiple sclerosis
- Amyotrophic lateral sclerosis
Additional interest extends to epilepsy, refractory status epilepticus, migraine, and neuropathic disorders with inflammatory or demyelinating features.
Hematology and Cell Therapy
Research involvement is strongly centered on acute leukemia, lymphoma, multiple myeloma, myelodysplastic syndromes, and related hematologic malignancies.
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Diffuse large B-cell lymphoma
- Multiple myeloma
Therapeutic interests also include allogeneic hematopoietic stem cell transplantation, graft-versus-host disease, and immune-based approaches for relapsed or refractory blood cancers.
Autoimmune and Inflammatory Diseases
The investigator is involved in trials across rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, Sjögren’s disease, and vasculitis.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Systemic sclerosis
- ANCA-associated vasculitis
Other areas include inflammatory myopathies, immune thrombocytopenia, myasthenia gravis, and cutaneous autoimmune disease.
Gastroenterology, Hepatology, and Metabolic Liver Disease
Clinical studies cover Crohn’s disease, ulcerative colitis, eosinophilic esophagitis, chronic liver disease, and metabolic dysfunction-associated steatohepatitis.
- Crohn’s disease
- Ulcerative colitis
- Hepatocellular carcinoma
- Metabolic dysfunction-associated steatohepatitis
Therapeutic focus also includes primary sclerosing cholangitis, alcohol-related liver disease, and cirrhosis linked to progressive fibrosis.
Cardiovascular, Respiratory, and Critical Care
Research activity extends to acute coronary syndrome, myocardial infarction, stroke, hypertension, pulmonary hypertension, and intensive care medicine.
- Acute myocardial infarction
- Ischemic stroke
- Pulmonary arterial hypertension
- Chronic obstructive pulmonary disease
Additional therapeutic domains include septic shock, acute kidney injury, pulmonary fibrosis, and severe respiratory infection.
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