Theodora S.
- Country
- Greece
- Department
- Department of Endocrinology
Research Overview
- Efficacy and Safety of Zenagamtide (NNC0487-0111) in Participants with Overweight or Obesity and Knee Osteoarthritis
- Effect of Muvalaplin on Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) and Atherosclerotic Cardiovascular Disease: A Phase 3 Randomized Trial
- Randomized Study of Cagrilintide + Semaglutide Combination vs Semaglutide Monotherapy for Weight Loss in Adults with Obesity (± Type 2 Diabetes)
Data & Insights
Has run more than one trial at 137 of 700 partner sites.
Specializations
Endocrine and Metabolic Disorders
Clinical research activity in endocrinology includes studies in type 2 diabetes, obesity, overweight, classic congenital adrenal hyperplasia, Cushing syndrome, acromegaly, and Graves’ disease, with interest in therapies that address hormonal balance and metabolic control.
- Type 2 diabetes
- Obesity and overweight
- Adrenal disorders
- Thyroid disease
Therapeutic focus also extends to glucocorticoid-sparing treatment and metabolic risk reduction in chronic endocrine conditions.
Hematologic Malignancies and Cellular Therapies
There is strong involvement in trials for multiple myeloma, acute myeloid leukemia, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma, marginal zone lymphoma, and chronic myeloid leukemia, including research on targeted agents, antibody-based regimens, and CAR T-cell therapy.
- Multiple myeloma
- Acute myeloid leukemia
- Lymphoma
- Cellular immunotherapy
Therapeutic interests include treatment of relapsed or refractory disease, maintenance strategies, and post-transplant disease control.
Inflammatory and Autoimmune Disease
Research activity covers Crohn’s disease, ulcerative colitis, coeliac disease, primary biliary cholangitis, and lupus, with emphasis on immune-mediated gastrointestinal and systemic inflammatory disorders.
- Crohn’s disease
- Ulcerative colitis
- Autoimmune liver disease
- Systemic autoimmune disease
Therapeutic domains include biologic maintenance treatment, symptom control, and long-term disease suppression in chronic inflammatory conditions.
Cardiovascular and Thrombotic Disease
Clinical trials include acute myocardial infarction, atherosclerotic cardiovascular disease, atrial fibrillation, stroke prevention, heart failure, hypertension, pulmonary arterial hypertension, and thrombotic thrombocytopenic purpura, reflecting a wide cardiovascular and hemostatic research profile.
- Myocardial infarction
- Atrial fibrillation
- Pulmonary arterial hypertension
- Thrombotic disorders
Therapeutic focus includes antithrombotic strategies, vascular risk reduction, and treatment of cardiopulmonary vascular disease.
Respiratory, Infectious, and Hepatic Conditions
Additional research interest is seen in chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, COVID-19, chronic hepatitis B, chronic hepatitis C, alcohol-related liver disease, and invasive candidiasis, covering both inflammatory and infectious disease settings.
- Chronic obstructive pulmonary disease
- Asthma
- COVID-19
- Chronic viral hepatitis
Therapeutic involvement includes respiratory inflammation, antiviral care, antifungal treatment, and management of chronic liver disease.
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