Tessa H.
- Country
- Germany
- Department
- Medizinische Klinik III
Research Overview
- Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Patients With Previously Treated TROP2-Positive Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
- Phase III Randomized Study of Rilvegostomig vs. Pembrolizumab Monotherapy in PD-L1-high Metastatic Non-small Cell Lung Cancer
- Evaluation of MK-1084 with Pembrolizumab and Berahyaluronidase Alfa versus MK-3475A with Pemetrexed/Platinum in KRAS G12C-Mutant Advanced NSCLC
Data & Insights
Has run more than one trial at 37 of 186 partner sites.
Specializations
Haematologic Malignancies
Clinical research in lymphoma, leukaemia, and related myeloid neoplasms forms a major part of this investigator’s work, with attention to treatment optimisation in both newly diagnosed and relapsed disease.
- Diffuse large B-cell lymphoma
- Chronic myeloid leukaemia
- Acute lymphoblastic leukaemia
- Myelodysplastic syndromes
- Multiple myeloma
The therapeutic focus includes cellular therapy, immunotherapy, and transplant-related oncology, reflecting involvement in innovation across blood cancers.
Solid Tumours and Hepatobiliary Oncology
Another key area is solid tumour oncology, especially cancers of the liver, biliary tract, ovary, lung, and breast, with a strong emphasis on advanced and unresectable disease.
- Hepatocellular carcinoma
- Cholangiocarcinoma
- Ovarian cancer
- Non-small cell lung cancer
- Melanoma
Research activity also spans gastrointestinal cancers and metastatic solid tumours, supporting development of newer systemic and locoregional treatment strategies.
Neurology and Neuro-oncology
The investigator is involved in studies of epilepsy, amyotrophic lateral sclerosis, and paediatric brain tumours, with additional interest in difficult-to-treat neurological disorders.
- Focal epilepsy
- Tuberous sclerosis complex-related epilepsy
- Amyotrophic lateral sclerosis
- Diffuse glioma
- Medulloblastoma
This area also includes developmental and epileptic encephalopathies and other central nervous system tumours, highlighting a therapeutic interest in neurologic innovation.
Autoimmune, Inflammatory, and Dermatologic Disease
Clinical work extends to immune-mediated inflammatory diseases, including psoriasis, atopic dermatitis, hidradenitis suppurativa, and systemic autoimmune rheumatic diseases.
- Psoriatic arthritis
- Atopic dermatitis
- Psoriasis
- Systemic lupus erythematosus
- Sjögren’s disease
Related interests include urticaria, vasculitis, and interstitial lung disease associated with autoimmunity, indicating a broad therapeutic engagement in chronic inflammatory conditions.
Cardiometabolic, Infectious, and Ophthalmic Disorders
The investigator also participates in studies across cardiovascular disease, metabolic risk, HIV-1 infection, and retinal disease, covering both chronic management and acute clinical risk.
- Atherosclerotic cardiovascular disease
- Heart failure
- HIV-1 infection
- Age-related macular degeneration
- Diabetic retinopathy
Additional activity includes stroke prevention, kidney injury, and haemophilia, reflecting involvement in therapeutic areas where treatment innovation remains clinically important.
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