Tatiana H. G.
- Country
- Spain
- Department
- Oncology
Research Overview
- Pharmacokinetic and Safety Evaluation of Oral Decitabine and Cedazuridine in Patients with Solid Tumors, Myelodysplastic Syndrome, or Acute Myeloid Leukemia with Hepatic Impairment
- Phase I Clinical Trial of TOS-358 in Adult Patients with Advanced Solid Tumors: Colorectal, Cervical, Endometrial, Gastric, Urothelial, Breast, Head and Neck, Ovarian, and NSCLC.
- Pharmacokinetic and Safety Evaluation of Oral Decitabine and Cedazuridine in Patients with Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Solid Tumors with Renal Impairment
Data & Insights
Has run more than one trial at 139 of 239 partner sites.
Specializations
Solid Tumor Oncology
Focus on a broad spectrum of solid tumors including gastrointestinal, thoracic, and gynecologic cancers.
- Colorectal cancer
- Non‑Small Cell Lung Cancer
- Breast cancer
- Ovarian cancer
- Gastric cancer
Encompasses both early‑stage and advanced disease settings.
Hematologic Malignancies
Investigates malignant disorders of the blood and bone marrow such as acute myeloid leukemia and related syndromes.
- Acute myeloid leukemia
- Myelodysplastic syndrome
- Chronic myelomonocytic leukemia
Includes studies of high‑risk and relapsed disease.
Targeted Molecular Oncology
Explores therapies directed at specific genetic alterations like KRAS G12C, HER2, and SMARCA4 mutations.
- KRAS‑mutated tumors
- HER2‑positive cancers
- SMARCA4‑deficient malignancies
- PIK3CA‑mutated solid tumors
- MTAP‑deleted cancers
Emphasizes precision medicine approaches.
Pain and Symptom Management
Addresses chronic pain conditions associated with cancer and non‑cancer etiologies, including diabetic peripheral neuropathic pain and knee osteoarthritis pain.
- Neuropathic pain
- Osteoarthritis pain
- Cancer‑related pain
Evaluates patient‑reported outcomes and quality of life.
Infectious Disease Immunology
Conducts studies on immune responses to viral pathogens, notably COVID‑19 vaccine boosters.
- SARS‑CoV‑2 vaccine efficacy
- Neutralising antibody responses
- Variant‑specific immunogenicity
Integrates immunogenicity assessments with safety monitoring.
Related Investigators
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