Tamas S.
- Country
- Hungary
- Department
- Nephrologiai
Research Overview
- A Parallel-group (2-Arm), Randomized, Double-blind, 12-week Trial to Evaluate the Efficacy and Safety of MC2-25 Cream and MC2-25 Vehicle in Subjects with Chronic Kidney Disease-associated Pruritus (CKD-aP)
- A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects with Immunoglobulin A Nephropathy
- A Study to Test How Well Alanyl Glutamine Cream Works and How Safe It Is for Adults with Itching Caused by Chronic Kidney Disease
Data & Insights
Has run more than one trial at 68 of 288 partner sites.
Specializations
Renal Disease Therapeutics
Focused on therapeutic strategies for Chronic Kidney Disease and its progression, including interventions to preserve renal function and reduce mortality.
- Sodium‑glucose co‑transporter 2 inhibition
- Mineralocorticoid receptor antagonists
- Renal protective agents
Research integrates real‑world data from two regional hospitals to evaluate outcome measures.
Glomerular and Autoimmune Nephritis
Investigates disease‑modifying treatments for IgA Nephropathy and Lupus Nephritis, emphasizing immunologic pathways and biomarker‑guided therapy.
- Targeted B‑cell depletion
- Complement inhibition
- Steroid‑sparing protocols
Collaborations with pathology units support histologic response assessment.
Hypertension and Cardiorenal Risk
Addresses Resistant Hypertension in patients with renal impairment and its impact on Cardiovascular Disease outcomes.
- Renin‑angiotensin system blockade
- Device‑based renal denervation
- Combination antihypertensive regimens
Data collection includes ambulatory blood pressure monitoring across affiliated sites.
Renal Transplantation and Immunomodulation
Explores immunosuppressive optimization and infection prophylaxis for recipients of Renal Transplantation.
- Calcineurin inhibitor minimization
- BCMA‑directed bispecific antibodies in post‑transplant myeloma
- Vaccination strategies for immunocompromised patients
Trials leverage the transplant program of the university hospital.
Renal‑Associated Dermatologic Symptoms
Evaluates therapies for CKD‑associated pruritus and related skin manifestations in dialysis populations.
- Kappa‑opioid receptor agonists
- Phototherapy adjuncts
- Topical neurokinin antagonists
Patient‑reported outcome measures drive efficacy endpoints.
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