Szilvia S.
- Country
- Hungary
- Department
- Reumatológiai Klinika
Research Overview
- Baricitinib Versus TNF Inhibitors for Venous Thromboembolism Risk in Rheumatoid Arthritis: Phase 3b/4 Active-Controlled Study
- Evaluation of Anifrolumab Efficacy and Safety in Systemic Sclerosis: A Phase III, Randomized, Double-Blind, Placebo-Controlled Study
- Efficacy and Safety Evaluation of Rosnilimab in Moderate to Severe Rheumatoid Arthritis: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study
Data & Insights
Has run more than one trial at 35 of 186 partner sites.
Specializations
Rheumatology and systemic autoimmune disease
Clinical activity is centered on inflammatory and autoimmune disorders treated within the Reumatológiai Klinika at the University of Debrecen, with emphasis on chronic immune-mediated disease control and organ involvement.
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Sjögren’s syndrome
- Systemic sclerosis
- Vasculitis
Therapeutic interest extends to disease-modifying approaches for autoimmune diseases with multisystem manifestations and persistent inflammatory activity.
Inflammatory joint and connective tissue disorders
Research involvement includes musculoskeletal inflammation and connective tissue disease phenotypes, particularly conditions associated with pain, stiffness, and functional limitation.
- Axial spondyloarthritis
- Psoriatic arthritis
- Idiopathic inflammatory myopathy
- Primary Sjögren’s disease
- Diffuse cutaneous systemic sclerosis
The therapeutic landscape also covers juvenile psoriatic arthritis and non-radiographic axial spondyloarthritis, reflecting interest in early and established inflammatory disease.
Immune-mediated skin and mucosal disease
Clinical trial activity spans chronic dermatologic inflammation and immune dysregulation, with focus on conditions that require targeted control of itch, plaques, and recurrent flares.
- Atopic dermatitis
- Plaque psoriasis
- Hidradenitis suppurativa
- Prurigo nodularis
- Vitiligo
Interest also includes chronic spontaneous urticaria and alopecia areata, highlighting therapeutic work across cutaneous immune-mediated disorders.
Gastrointestinal and hepatobiliary inflammation
Research spans chronic inflammatory and cholestatic diseases affecting the gut and liver, with attention to symptom burden, disease progression, and long-term disease control.
- Crohn’s disease
- Ulcerative colitis
- Primary sclerosing cholangitis
- Primary biliary cholangitis
- Metabolic dysfunction-associated steatotic liver disease
Therapeutic interest also includes hepatic encephalopathy and cirrhosis, linking inflammatory medicine with hepatology-focused care.
Cardiometabolic and multisystem inflammatory risk
Additional trial involvement reflects interest in conditions where inflammation intersects with vascular, metabolic, and renal complications.
- Atherosclerotic cardiovascular disease
- Obesity
- Type 2 diabetes mellitus
- Chronic kidney disease
- Hyperlipidemia
This includes therapeutic attention to cardiovascular disease risk reduction and systemic complications associated with chronic inflammatory disorders.
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