Szabolcs M.
- Country
- Hungary
- Department
- II. sz. Belgyógyászati Klinika és Kardiológiai Központ, Hematológiai Osztaly
Research Overview
- Blinatumomab and Combination Therapy Versus Standard of Care in Older Adults With Newly Diagnosed Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia
- Phase 2 Open-Label Study of Venetoclax, Carfilzomib, and Dexamethasone in Relapsed/Refractory Multiple Myeloma Patients
- Phase 3 Randomized Study of Epcoritamab Plus R-CHOP Versus R-CHOP in Newly Diagnosed Diffuse Large B-Cell Lymphoma Patients
Data & Insights
Has run more than one trial at 121 of 271 partner sites.
Specializations
Cardiovascular Medicine
Clinical research includes atherosclerotic cardiovascular disease, acute coronary syndrome, heart failure, atrial fibrillation, hypertension, dyslipidemia, and thromboembolic disease, with attention to prevention and risk reduction in high-risk patients.
- Heart failure with preserved or mildly reduced ejection fraction
- Cardiovascular event prevention
- Hyperlipidemia and elevated lipoprotein(a)
- Anticoagulation-related stroke prevention
Therapeutic interest also extends to pulmonary arterial hypertension, cardiomyopathy, and vascular outcomes linked to systemic inflammation.
Autoimmune and Inflammatory Disease
The investigator is involved in studies of rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, lupus nephritis, Sjögren's syndrome, systemic sclerosis, and vasculitis, reflecting a strong focus on immune-mediated disease.
- Psoriasis and psoriatic arthritis
- Systemic lupus erythematosus
- Polymyalgia rheumatica
- Behçet’s syndrome and myositis
Additional activity includes atopic dermatitis, chronic spontaneous urticaria, vitiligo, and prurigo nodularis.
Gastroenterology and Hepatology
Research activity covers Crohn's disease, ulcerative colitis, inflammatory bowel disease, primary biliary cholangitis, and hepatitis B, with a clear therapeutic interest in chronic inflammatory and immune-driven digestive disorders.
- Moderately to severely active Crohn’s disease
- Ulcerative colitis
- Fistulizing perianal Crohn’s disease
- Primary biliary cholangitis
There is also involvement in Clostridioides difficile infection and short bowel syndrome.
Oncology and Hematologic Malignancies
The clinical portfolio includes bladder cancer, breast cancer, colorectal cancer, renal cell carcinoma, melanoma, and head and neck squamous cell carcinoma, alongside multiple hematologic malignancies.
- Diffuse large B-cell lymphoma
- Chronic lymphocytic leukemia
- Multiple myeloma
- Acute myeloid leukemia and myelodysplastic syndromes
Therapeutic interest also includes prostate cancer, ovarian cancer, and Ewing sarcoma.
Metabolic, Renal, and Other Chronic Disorders
Additional research spans type 2 diabetes, obesity, chronic kidney disease, IgA nephropathy, and diabetic complications, with emphasis on long-term cardiometabolic and renal risk.
- Diabetic macular edema
- Diabetic peripheral neuropathy
- Proteinuria and kidney disease
- Obesity-related cardiovascular risk
Interest also extends to chronic obstructive pulmonary disease, asthma, major depressive disorder, and Tourette’s disorder.
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