Sven S.
- Country
- Austria
- Department
- Department of Ear, Nose and Throat Disease
Research Overview
- Comparative Effectiveness of Tezepelumab versus Dupilumab in Patients with Chronic Rhinosinusitis with Nasal Polyps: A Real-World Study
- Evaluation of Dupilumab on Nasal Epithelial Barrier Function in Chronic Rhinosinusitis with Nasal Polyps: An Exploratory Pilot Study
- Phase 3 Evaluation of Itepekimab Efficacy and Safety in Adults with Inadequately-Controlled Chronic Rhinosinusitis with Nasal Polyps
Data & Insights
Has run more than one trial at 3 of 51 partner sites.
Specializations
Otology and Sudden Sensorineural Hearing Loss
The investigator concentrates on therapeutic strategies for acute auditory impairment and inner‑ear disorders.
- idiopathic sudden sensorineural hearing loss
- acquired angioedema due to C1 inhibitor deficiency
- autoimmune inner‑ear disease
- vestibular dysfunction associated with inflammatory conditions
- sensorineural hearing loss secondary to systemic lupus erythematosus
Research emphasizes rapid restoration of auditory function and protection of cochlear structures.
Chronic Rhinosinusitis and Nasal Polyps
Focused on long‑term management of persistent sinonasal inflammation and polyp formation.
- chronic rhinosinusitis with nasal polyps
- chronic rhinosinusitis without nasal polyps
- allergic rhinoconjunctivitis
- refractory sinus disease in immunocompromised patients
- post‑operative sinus healing after endoscopic sinus surgery
Therapeutic aims include reducing mucosal edema, preventing recurrence, and improving airway patency.
Head and Neck Oncology
Engaged in clinical studies targeting malignant tumors of the upper aerodigestive tract.
- head and neck squamous cell carcinoma
- oropharyngeal cancer
- laryngeal carcinoma
- salivary gland neoplasms
- advanced nasopharyngeal carcinoma
Efforts focus on integrating systemic therapies with organ‑preserving surgical techniques.
Allergic and Inflammatory Upper Airway Disease
Investigates immune‑mediated conditions affecting the nasal cavity and pharynx.
- atopic dermatitis with nasal involvement
- allergic fungal sinusitis
- immune‑mediated rhinitis
- chronically inflamed adenoidal tissue
- environmental trigger‑related upper airway inflammation
Therapeutic development emphasizes biologic agents and targeted anti‑inflammatory pathways.
Voice, Swallowing, and Laryngeal Function
Addresses disorders that compromise phonation and deglutition.
- functional voice disorders
- laryngopharyngeal reflux affecting vocal folds
- post‑intubation laryngeal injury
- neuromuscular dysphagia in autoimmune disease
- vocal fold paralysis secondary to systemic illness
Clinical work aims to restore vocal quality and safe swallowing through pharmacologic and rehabilitative measures.
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