Sini L.
- Country
- Finland
- Department
- Helsinki University Hospital, Comprehensive Cancer Centre
Research Overview
- Phase 3 Randomized Study of Mezigdomide, Bortezomib, and Dexamethasone vs. Pomalidomide, Bortezomib, and Dexamethasone in Relapsed/Refractory Multiple Myeloma
- Phase 3 Randomized Study of Iberdomide, Daratumumab, and Dexamethasone vs. Daratumumab, Bortezomib, and Dexamethasone in Relapsed/Refractory Multiple Myeloma
- A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Therapy after Autologous Stem Cell Transplantation (ASCT) in Participants with Newly Diagnosed Multiple Myeloma (NDMM) (EXCALIBER-Maintenance)
Data & Insights
Has run more than one trial at 46 of 170 partner sites.
Specializations
Hematologic Oncology
The investigator specializes in the treatment of multiple myeloma, with particular emphasis on managing cases that have shown resistance to previous treatments or experienced disease recurrence.
- Relapsed/Refractory Multiple Myeloma
- Novel Therapeutic Combinations
- Disease Progression Management
Their research focuses on evaluating innovative therapeutic approaches for patients with refractory multiple myeloma, exploring combinations of established and emerging treatments.
Treatment Innovation
The investigator explores novel drug combinations including immunomodulatory agents and proteasome inhibitors for blood cancer treatment.
- Combination Therapy Approaches
- Treatment Resistance
- Therapeutic Innovation
Their work encompasses the evaluation of comparative treatment efficacy in resistant disease settings.
Clinical Outcomes
The investigator focuses on measuring progression-free survival and treatment effectiveness in advanced hematologic malignancies.
- Disease Progression Assessment
- Treatment Response Evaluation
- Long-term Outcome Analysis
Their research emphasizes the assessment of therapeutic interventions in improving patient outcomes for blood cancer.
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