Steffen H.
- Country
- Germany
- Department
- Clinical Services
Research Overview
- Phase I Evaluation of Vamorolone Pharmacokinetics, Safety, and Pharmacodynamics in Healthy Male Volunteers for Duchenne and Becker Muscular Dystrophy
- First-in-Human Study of BAY 3620122, a Novel Therapeutic for Vasodilatory Shock, Evaluating Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Volunteers
- Phase I Study Evaluating Safety and Immunogenicity of a Multivalent Gonorrhea Vaccine in Healthy Adults
Data & Insights
Has run more than one trial at 1 of 2 partner sites.
Specializations
Metabolic and Weight Management
Clinical research activity includes therapies for obesity, overweight, type 2 diabetes mellitus, and post-bariatric hypoglycaemia, with attention to treatment options that address metabolic regulation and appetite-related disease.
- Obesity and overweight
- Type 2 diabetes mellitus
- Post-bariatric hypoglycaemia
Interest also extends to vasomotor symptoms and other hormone-dependent conditions that overlap with metabolic and endocrine care.
Cardiovascular and Thrombotic Disorders
The investigator is involved in studies across cardiac arrhythmia, prevention of ischemic stroke, prevention of thromboembolic events, pulmonary hypertension due to left heart disease, and vasodilatory shock, reflecting a broad cardiovascular focus.
- Cardiac arrhythmia
- Ischemic stroke prevention
- Thromboembolic disease
- Pulmonary hypertension
- Vasodilatory shock
Additional interest is evident in cardiac repolarization and drug-drug interactions relevant to cardiovascular pharmacology.
Renal, Hematologic, and Transplant Medicine
Research involvement covers Alport syndrome, symptomatic anaemia in chronic renal failure, and prophylaxis of transplant rejection in liver, kidney, and heart allograft settings, linking renal, hematologic, and transplant therapeutics.
- Alport syndrome
- Chronic renal failure-associated anaemia
- Transplant rejection prophylaxis
- Allograft rejection treatment
Work in this area also includes evaluation of epoetin alfa and other approaches used to support red blood cell production.
Neurology, Pain, and Musculoskeletal Conditions
Clinical interests include migraine, acute and chronic musculoskeletal conditions, mood disorders, and inherited muscle disease such as Duchenne muscular dystrophy and Becker muscular dystrophy.
- Migraine
- Musculoskeletal pain and inflammation
- Mood disorders
- Duchenne muscular dystrophy
- Becker muscular dystrophy
This portfolio also touches on vasomotor symptoms and broader symptom-focused therapeutic development.
Infectious, Parasitic, and Pharmacology Studies
The investigator participates in research on onchocerciasis, soil-transmitted helminth infection, and other parasitic diseases, alongside healthy volunteer studies supporting early therapeutic evaluation and drug metabolism assessment.
- Onchocerciasis
- Soil-transmitted helminth infection
- Healthy volunteer pharmacology
- Drug-drug interaction
Related work includes pharmacokinetics, bioavailability, and cardiac repolarization studies that support therapeutic development across multiple disease areas.
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