Stefano D. G.
- Country
- Italy
- Department
- Azienda Ospedaliero-Universitaria Di Cagliari
Research Overview
- Long-term safety and efficacy of subcutaneous lunsekimig in adults with asthma: An open-label extension study
- Phase 3b/4 Randomized Double‑Blind Study of Depemokimab 100 mg SC Q26 weeks vs Placebo on Exacerbations and Lung‑Function Decline in Adults/Adolescents with Type 2 Asthma
- Evaluation of Long-Term Safety of Salbutamol Sulfate via MDI with Propellants HFA-152a and HFA-134a in Adults with Asthma
Data & Insights
Has run more than one trial at 121 of 287 partner sites.
Specializations
Respiratory and Airway Disease
Clinical research activity includes asthma across severe asthma, eosinophilic asthma, and moderate-to-severe asthma, with interest in treatment optimization, symptom control, and maintenance reduction strategies. The investigator is also involved in studies addressing acute respiratory distress syndrome and broader airway management.
- Severe asthma
- Eosinophilic asthma
- Asthma medication reduction
- Acute respiratory distress syndrome
Additional therapeutic focus extends to inhaled treatment approaches and biologic-based control of airway inflammation.
Gastroenterology and Inflammatory Bowel Disease
The investigator is active in Crohn’s disease and ulcerative colitis, including moderately to severely active Crohn’s disease, ulcerative colitis, and rectal involvement. Research interest also covers immune-mediated intestinal inflammation and endoscopic disease control.
- Crohn’s disease
- Ulcerative colitis
- Moderately to severely active Crohn’s disease
- Ulcerative rectal colitis
Therapeutic activity includes targeted immunomodulation and combination strategies for chronic intestinal inflammation.
Oncology and Precision Cancer Therapy
Research involvement spans multiple solid tumors, with strong emphasis on metastatic colorectal cancer, colorectal cancer, non-small cell lung cancer, gastric cancer, biliary tract cancer, and hepatocellular carcinoma. The investigator also contributes to studies in breast cancer, urothelial cancer, renal cell carcinoma, ovarian cancer, and anal canal squamous cell carcinoma.
- Metastatic colorectal cancer
- Non-small cell lung cancer
- Gastric and gastroesophageal junction cancer
- Biliary tract cancer
Key therapeutic interests include targeted therapy, immunotherapy, and biomarker-guided treatment selection in advanced malignancies.
Dermatology, Allergy, and Immune-Mediated Disease
Clinical trial work includes moderate to severe plaque psoriasis, atopic dermatitis, psoriatic arthritis, nonsegmental vitiligo, actinic keratosis, and thyroid eye disease. The investigator is also involved in hereditary angioedema, acquired angioedema, and systemic lupus erythematosus.
- Moderate to severe plaque psoriasis
- Atopic dermatitis
- Psoriatic arthritis
- Nonsegmental vitiligo
Therapeutic interests center on immune pathway modulation in inflammatory skin and systemic autoimmune disorders.
Autoimmune, Neurologic, and Metabolic-Surgical Conditions
Additional research spans rheumatoid arthritis, systemic sclerosis-associated interstitial lung disease, connective tissue diseases, focal epilepsy, stroke, insomnia disorder, and endometriosis-related pain. The investigator also participates in studies of Graves’ disease, vascular disease, and pancreatic ductal adenocarcinoma.
- Rheumatoid arthritis
- Systemic sclerosis-associated interstitial lung disease
- Focal epilepsy
- Endometriosis-related pain
Therapeutic focus includes immune-mediated disease control, neurologic symptom management, and selected areas of vascular and perioperative care.
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