Sosana D.
- Country
- Greece
- Department
- Hematology and Lymphoma Clinic – Bone Marrow Transplant Unit
Research Overview
- Phase 2, multicenter, open‑label study of extended‑dosing belantamab mafodotin in combination therapy for relapsed/refractory multiple myeloma
- Phase 1/2 Study of REGN17372 in Combination with Linvoseltamab in Participants with Relapsed/Refractory Multiple Myeloma
- Phase 3 Randomized Study of JNJ-79635322 Versus Teclistamab in Relapsed or Refractory Multiple Myeloma After Prior PI, IMiD, and Anti-CD38 Therapy
Data & Insights
Has run more than one trial at 240 of 419 partner sites.
Specializations
Hematologic Malignancies
The clinical research portfolio centers on multiple myeloma, acute myeloid leukemia, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, and related non-Hodgkin lymphoma subtypes. It also includes studies in follicular lymphoma, marginal zone lymphoma, small lymphocytic lymphoma, and Philadelphia chromosome-positive leukemia.
- Relapsed and refractory plasma cell disorders
- Newly diagnosed myeloma
- Leukemia and lymphoma
- Cellular and antibody-based hematologic therapies
Research activity is closely aligned with the Bone Marrow Transplantation Unit, with interest in treatment-resistant disease, post-transplant settings, and advanced hematology care.
Gastroenterology and Inflammatory Bowel Disease
Another major area of interest involves Crohn's disease and ulcerative colitis, including moderate-to-severe and refractory forms, as well as fistulizing and maintenance-focused disease management. The portfolio also extends to broader inflammatory bowel disease care.
- Crohn’s disease
- Ulcerative colitis
- Endoscopic and symptomatic disease control
- Long-term inflammatory bowel disease maintenance
This area reflects sustained involvement in therapies for chronic intestinal inflammation and treatment response in difficult-to-control gastrointestinal disease.
Respiratory Disease and Pulmonary Vascular Disorders
The investigator is active in chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis, and pulmonary arterial hypertension. The portfolio also includes pulmonary hypertension associated with interstitial lung disease and respiratory complications linked to inflammatory or infectious conditions.
- COPD
- Asthma with type 2 inflammation
- Pulmonary arterial hypertension
- Interstitial lung disease-related pulmonary hypertension
Therapeutic interest also covers respiratory recovery after infection and lung function preservation in chronic airway disease.
Cardiovascular and Thrombotic Medicine
Clinical trial involvement includes acute myocardial infarction, atherosclerotic cardiovascular disease, atrial fibrillation, stroke prevention, and heart failure. The investigator is also engaged in studies addressing hypertension, symptomatic hypertrophic cardiomyopathy, and thrombotic thrombocytopenic purpura.
- Myocardial infarction and secondary prevention
- Stroke and embolic risk reduction
- Arrhythmia-related thromboprophylaxis
- Cardiomyopathy and vascular inflammation
This domain includes therapies aimed at reducing thrombotic events and improving outcomes in high-risk cardiovascular disease.
Transplantation, Infection, and Immune-Mediated Disease
Additional research spans graft-versus-host disease, hematopoietic stem cell transplant-associated complications, invasive candidiasis, COVID-19, hepatitis B, and HIV infection. The portfolio also includes immune-mediated and inflammatory conditions such as primary biliary cholangitis, hypereosinophilic syndrome, and type 2 diabetes in selected therapeutic contexts.
- Post-transplant immune complications
- Serious fungal and viral infections
- Chronic viral hepatitis
- Immune dysregulation and systemic inflammation
Trial activity in this area reflects engagement with complex conditions requiring targeted immunologic, anti-infective, and supportive therapeutic strategies.
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